• The synthesis and characterization of macrocyclic ligands and investigations of the thermo and photo reactivity of their transition metal ion complexes 

  Mackay, Ian Douglas (2017-06-28)

  The mono protection of 1,4,7-triazacyclononane ([9]-aneN₃) was accomplished efficiently through the formation of an orthoamide derivative. The orthoamide was used to form three mono protected derivatives of [9]-aneN₃ which ...
• Deprotonated aza-crown ligands as simple and effective alternatives to C₅Me₅ in group 3, 4, and lanthanide chemistry 

  Lee, Lawrence Way Mung (2017-06-26)

  The ability of a deprotonated aza-crown ether to allow isolation of soluble lanthanide and yttrium complexes has been investigated. A convenient route to these complexes has been demonstrated by the protonolysis reactions ...
• The Dynamics of benzylic radical pairs in organized media : binding and mobility 

  Kleinman, Mark Howard (2017-06-23)

  Through the use of laser flash photolysis and product studies, the photochemistry of dibenzyl ketone and its derivatives in SDS micelles shows that these aggregates impart some constraint on the dynamics of benzylic radical ...
• Synthesis, characterization and group modification of carbosilane based dendrimers 

  Hooper, Richard (2017-06-21)

  Carbosilane dendrimers have been prepared via iterative hydrosilylation/alkenylation reactions using a variety of chlorosilanes (HSiMe₃₋nC1n)and alkenyl nucleophiles (CH₂=CHCH₂MgBr and CH₂=CHMgBr). Characterization by ...
• Flexible ditopic receptors 

  Zeng, Binqui (2017-06-05)

  This thesis comprises three parts united by a single theme: development of flexible ditopic receptors. In part 1, two bis(crown ether)s were synthesized and their binding selectivities with alkali, alkaline earth and ...
• The use of 10b, 10c-dimethyldihydropyrene (DHP) as a probe to study the Mills-Nixon effect 

  Lau, Yee-Kwan (Danny) (2017-05-12)

  The syntheses of many cycloalkene and cycloalkeneone annelated DHPs have been achieved. A late ring formation approach was used to synthesize the dicycloalkeneone annelated DHP 63 (Scheme 4) and the unsymmetrical ...
• Intramolecular interactions in rhodium monoxide and halogen azides 

  Jensen, Roy Henry (2017-05-05)

  Part A. Vibronic transitions of rhodium monoxide (Rh¹⁶O and Rh¹⁸O) were observed in the 380 to 700 nm region. Laser-induced fluorescence identified two ²[pi]r - X⁴Σ⁻ progressions with origins at {15 667, 15 976} and {15 ...
• Real-time mass spectrometric analysis of catalytic reaction mechanisms 

  Yunker, Lars Peter Erasmus (2017-05-01)

  Mass spectrometry was used to study two disparate transformations: in an applied project, the supposed degradation of perfluorooctanesulfonate (PFOS); and in a fundamental study, the Suzuki-Miyaura (SM) reaction was ...
• The syntheses and photochromic properties of several substituted and condensed benzo[e]dimethyl-dihydropyrenes 

  Wang, Yunxia (2017-05-01)

  The symmetric multistate photo-switchable molecule 72, which contains two DHP units with a dibenzocyclophane as a spacer, was successfully synthesized by different routes using aryne-furan type Diels-Alder reactions. In ...
• Selective analysis of petroleum fractions by mass spectrometry 

  Zhu, Haoxuan (2017-03-22)

  Electrospray ionization mass spectrometry (ESI-MS) is a fast and sensitive technique that is ideal for detecting low concentration species of interest within complex mixtures. Because ESI-MS simply transfers charged species ...
• Label-free plasmonic detection using nanogratings fabricated by laser interference lithography 

  Hong, Koh Yiin (Plasmonics, 2017-01-02)

  Plasmonics techniques, such as surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS), have been widely used for chemical and biochemical sensing applications. One approach to excite surface plasmons ...
• Curcumin-loaded block copolymer nanoparticles for drug delivery using microfluidics 

  Chen, Ruyao (2017-03-09)

  This thesis includes three stages of experiments. The goal of the thesis was to prepare nanoparticle-encapsulated curcumin for the purpose of drug delivery. The first step was the nanoparticle preparation. The self-assembly ...
• Microfluidic synthesis of drug-loaded block copolymer nanoparticles and its effect on drug delivery 

  Cao, Yimeng (2017-01-23)

  In this thesis, I used a two-phase gas-liquid segmented microfluidic platform to synthesize drug-loaded block copolymer nanoparticles. In Chapter 2 and 3, the anti-cancer drug 7-ethyl-10-hydroxycamptothecin (SN-38) was ...
• The study of ruthenium(II) half-sandwich phosphido complexes containing pentamethylcyclopentadienyl (Cp*) ligand 

  Yang, Jin (2016-12-20)

  Previous work in the Rosenberg group showed that the half-sandwich complexes Ru(η5-indenyl)Cl(PR2H)(PPh3) (2i), where R = cyclohexyl (Cy), isopropyl (Pri), phenyl (Ph), para-tolyl (Tolp), react with the strong, bulky base ...
• Exploring the binding of small guest molecules in sodium deoxycholate hydrogels 

  Seyedalikhani, Mehraveh (2016-11-03)

  Bile salts are supramolecules with amphiphilic properties. Bile salts form aggregates in aqueous solutions. The primary aggregates of bile salts are hydrophobic and the secondary aggregates which form at higher concentrations ...
• Platinum oxide reduction kinetics on polycrystalline platinum electrodes 

  Qile, Geer (2016-09-26)

  A kinetic study on polycrystalline platinum (Pt) in sulphuric acid is presented. An electrochemical kinetic mechanism of Pt oxide reduction and surface oxide structures are proposed. The reduction reaction was studied by ...
• Cytotoxic methylthioadenosine analogues 

  Doerksen, Thomas (2016-09-09)

  The gene for methylthioadenosine phosphorylase (MTAP) is absent in almost 30% of cancers, opening a door for selective chemotherapy. One strategy to target the absence of MTAP involves the design of a cytotoxic methylthioadenosine ...
• Reaction monitoring using real-time methods 

  Wu, Yang (2016-08-24)

  Electrospray ionization mass spectrometry (ESI-MS) is a powerful method to monitor organometallic reactions. It is fast at generating spectrum, soft to fragile organometallic compounds and sensitive to intermediates in low ...
• Mechanistic diversity in the guest binding with cucurbit[7]uril or octa acid complexes 

  Thomas, Suma Susan (2016-07-05)

  Supramolecular systems comprised of non-covalent interactions are reversible in nature. This intrinsic reversibility of these systems is essential in achieving several functions, making it crucial to understand the dynamics ...
• Rapid quantitative and qualitative screening of naphthenic acids in contaminated waters using condensed phase membrane introduction mass spectrometry 

  Letourneau, Dane Rene (2016-05-20)

  Naphthenic acids (NA) are a highly complex mixture of aliphatic carboxylic acids that may contain multiple rings and unsaturated double bonds, and are a subset of the naphthenic acid fraction components (NAFC), which can ...

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