The formation and patterns of a monolayer are determined by the interplay of two fundamental interactions, adsorbate-substrate and intermolecular interactions. The binding strength between adsorbate and substrate affects ...
Condensed phase membrane introduction mass spectrometry (CP-MIMS) is a direct, in situ analysis technique that is well suited to persistent organic pollutants, pesticides, and other small molecules. In CP-MIMS, neutral ...
Role of N-methylated lysines (K) and arginines (R) was underappreciated for a long time before the turn of the century. With the help of new emerging technologies, their crucial role in chromatin regulation was established ...
Dicyclopentadiene (DCPD), a tricyclic olefin, is available from the C5 fraction of petroleum feedstocks. Owing to its high reactivity (due to the presence of a strained alkene), low cost, and lack of other commercial uses, ...
Reactions can be monitored in real-time or off-line for qualitative and quantitative information on reaction systems under study. The work presented in this dissertation was focused on the application of reaction monitoring ...
In this thesis, the reactivity and synthesis of methylalumoxane (MAO) via electrospray ionization mass spectrometry (ESI-MS) was investigated. The olefin polymerization catalyst [Cp2Zr(μ-Me)2AlMe2]+ [B(C6F5)4]− was also ...
Silicone rubber is a promising candidate for the next generation of electrical insulators on account of the prolonged hydrophobicity of the polymers. However, microalgae biofouling is always a concern for high voltage ...
An array of carbazole-bis(azole) (CzTR and CzTrR, Cz = carbazole, T = tetrazole, Tr = triazole, R = Me, iPr, Bz and CH2Mes) pincer ligands were synthesized and fully characterized by NMR, X-ray crystallography and high ...
Microfluidic flow devices coupled with quantitative Raman spectroscopy are able to provide a deep insight into the reaction mechanism and kinetics of electrocatalytic reactions. With a microfluidic flow device made with ...
The kinetics of the oxidation of platinum metal have long been a topic of interest in the field of electrochemistry. Using a combination of cyclic voltammetry, potential step experiments, and sweep-hold experiments, this ...
This dissertation presents a collection of biological simulations and predictions in collaboration with experiment to support and elucidate the trends observed in various protein–ligand systems. Within the model systems, ...
Polymer nanoparticles (PNPs) that exhibit selective stimuli-responsive degradation and drug release at tumor sites are promising candidates in the development of smart nanomedicines. In this thesis, we demonstrate a ...
The interconversion of α- and β-Ni(OH)₂ was studied using cyclic voltammetry and dynamic electrochemical impedance (dEIS). Holding experiments were done at 0.5 V, 0.6 V, 0.8 V and 1.0 V while subsequent cathodic holds were ...
Contrast agents for magnetic resonance imaging (MRI) are but one of a variety of nanosystems that have incredible potential for the detection and diagnosis of cancer. Nanosystems share a common disadvantage: they are quickly ...
Systems chemistry is an emerging field of chemistry that studies complex mixtures of molecules that give rise to emergent properties that are not always predictable when studying the components of the mixtures in isolation. ...
Sulfones are useful bioisosteres in drug discovery, and have an unusual ability to engage in binding with both polar and nonpolar regions of target proteins. Despite this, they have seen limited use in drug-screening ...
Lysine methylation is a post-translational modification that regulates a large array of functionally diverse processes that are vital for cellular function. The role of methylation is best characterized on histone proteins ...
Surface self-assembly, the spontaneous aggregation of molecules into ordered, sta-
ble, noncovalently joined structures in the presence of a surface, is of great importance
to the bottom-up manufacturing of materials ...
Nature has inspired chemists to develop complex assemblies that perform functions in biologically relevant solutions. Yet this is not a trivial task. Not only does water act as a competitive medium but the salts that are ...
Understanding bacterial adhesion and biofilm formations on abiotic surfaces are important biological processes that affect the growth of bacteria, with its far-spreading impacts on in everyday life, either as a benefactor ...