Reactivity of [Pt2(μ-S)2(PPh3)4] towards activated aliphatic bromoacyl electrophiles: Formation of mono-, homodi-, heterodi- and intramolecular-bridged alkylated products
Date
2016
Authors
Ujam, Oguejiofo T.
Janusson, Eric
Stoddard, Rhonda L.
Mclndoe, J. Scott
Oliver, Allen G.
Odo, Paschal C.
Ogbonna, Ogbonna C.
Journal Title
Journal ISSN
Volume Title
Publisher
Inorganica Chimica Acta
Abstract
Reactions of [Pt2(μ-S)2(PPh3)4] with activated aliphatic bromoacyl alkylating agents BrCH2C(O)C(CH3)3, BrCH2C(O)CH2CH3 and BrCH2C(O)C(O)CH2Br, were investigated by electrospray ionization mass spectrometry (ESI-MS) in real time using pressurized sample infusion (PSI). The laboratory scale reactions gave the mono-, dicationic and bridged, μ-thiolate complexes [Pt2(μ-S){μ-SCH2C(O)C(CH3)3}(PPh3)4]+, [Pt2{μ-SCH2C(O)CH2CH3}2 (PPh3)4]2+ and [Pt2{μ-SCH2C(O)C(O)CH2S}(PPh3)4]2+. Sequential reactions of [Pt2(μ-S)2 (PPh3)4] with BrCH2C(O)C(CH3)3 and BrCH2C(O)CH2CH3 yielded the heterodialkylated complex [Pt2{μ-SCH2C(O)C(CH3)3}{μ-SCH2C(O)CH2CH3}(PPh3)4]2+. The products were isolated as the [BPh4]– or [PF6]– salts and characterized by ESI-MS, IR, 1H and 31P NMR spectroscopy and single-crystal X-ray crystallography.
Description
Keywords
mass spectrometry, alkylation, platinum(II) complexes, X-ray crystallography
Citation
Ujam, O. T., Janusson, E., Stoddard, R., Mclndoe, J. S., Oliver, A. G., Odo, P. C., & Ogbonna, O. C. (2016). Reactivity of [Pt2(μ-S)2(PPh3)4] towards activated aliphatic bromoacyl electrophiles: Formation of mono-, homodi-, heterodi- and intramolecular-bridged alkylated products. Inorganica Chimica Acta, 450, 92-100.