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Do Pair-Fed Diets have Sex-Specific Influences on Bi-Directional Plasticity in the Medial Perforant Path of the Dentate Gyrus?

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dc.contributor.author Suesser, Konrad
dc.contributor.author Fontaine, Christine J.
dc.contributor.author Christie, Brian R.
dc.date.accessioned 2018-04-13T20:40:38Z
dc.date.available 2018-04-13T20:40:38Z
dc.date.copyright 2018 en_US
dc.date.issued 2018-04-13
dc.identifier.uri https://dspace.library.uvic.ca//handle/1828/9219
dc.description.abstract Alcohol is a teratogen that can lead to a range of developmental problems in offspring known as fetal alcohol spectrum disorders (FASDs). Ethanol exposure during pregnancy, known more formally as Pre-natal ethanol exposure (PNEE), especially affects an infant’s ability to learn and form memories, which are functions commonly associated with the hippocampus, a subcortical structure. The efficacy of neural transmission and synaptic plasticity in the brain is determined by both increasing and decreasing synaptic strength of neurotransmission, known as long-term potentiation (LTP) and long-term depression (LTD), respectively. Using in-vitro electrophysiology techniques, I carried out high-frequency stimulation (HFS) and low-frequency stimulation (LFS) protocols in the medial perforant path of the dentate gyrus, within the hippocampus, to analyze differences in LTP and LTD of male and female pair-fed rats. en_US
dc.description.sponsorship This project was supported by the Jamie Cassels Undergraduate Research Award. en_US
dc.language.iso en en_US
dc.subject Fetal alcohol spectrum disorder en_US
dc.subject FASD en_US
dc.subject Hippocampus en_US
dc.subject electrophysiology en_US
dc.subject Medial Perforant path en_US
dc.subject Dentate Gyrus en_US
dc.subject LTP en_US
dc.subject long-term potentiation en_US
dc.subject LTD en_US
dc.subject long-term depression en_US
dc.subject synaptic plasticity en_US
dc.subject learning en_US
dc.subject memory en_US
dc.subject Neuroscience en_US
dc.subject Medical science en_US
dc.subject Neurobiology en_US
dc.title Do Pair-Fed Diets have Sex-Specific Influences on Bi-Directional Plasticity in the Medial Perforant Path of the Dentate Gyrus? en_US
dc.type Poster en_US
dc.description.scholarlevel Undergraduate en_US
dc.description.reviewstatus Reviewed en_US


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