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Browsing by Author "Da Silva, Melissa"

Browsing by Author "Da Silva, Melissa"

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  • Butler-Cole, Christine; Wagner, Mary J; Da Silva, Melissa; Brown, Gordon D; Burke, Robert D; Upton, Chris (BioMed Central, 2007-07-24)
    Background: Profilins are critical to cytoskeletal dynamics in eukaryotes; however, little is known about their viral counterparts. In this study, a poxviral profilin homolog, ectromelia virus strain Moscow gene 141 ...
  • Da Silva, Melissa; Upton, Chris (BioMed Central, 2005-04-11)
    Background Poxviruses are important both as pathogens and as vaccine vectors. Poxvirus genomes (150–350 kb) consist of a single linear dsDNA molecule; the two polynucleotide strands are joined by short hairpin loops. ...
  • Da Silva, Melissa; Upton, Chris (BioMed Central, 2005-02-18)
    Background: Clusters or runs of purines on the mRNA synonymous strand have been found in many different organisms including orthopoxviruses. The purine bias that is exhibited by these clusters can be observed using a ...