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Browsing by Author "Gudavicius, Geoff"

Browsing by Author "Gudavicius, Geoff"

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  • Leung, Andrew; Jardim, Francy-Pesek; Savic, Neda; Monneau, Yoan R.; González-Romero, Rodrigo; Gudavicius, Geoff; Eirin-Lopez, Jose M.; Bartke, Till; Mackereth, Cameron D.; Ausió, Juan; Nelson, Christopher J. (Scientific Reports, 2017)
    The nucleoplasmin family of histone chaperones is identified by a pentamer-forming domain and multiple acidic tracts that mediate histone binding and chaperone activity. Within this family, a novel domain organization was ...
  • Dilworth, David; Upadhyay, Santosh K.; Bonnafous, Pierre; Edoo, Amiirah Bibi; Bourbigot, Sarah; Pesek-Jardim, Francy; Gudavicius, Geoff; Serpa, Jason J.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Nelson, Christopher J.; Mackereth, Cameron D. (Nucleic Acids Research, 2017)
    Prolyl isomerases are defined by a catalytic domain that facilitates the cis–trans interconversion of proline residues. In most cases, additional domains in these enzymes add important biological function, including ...
  • Makepeace, Karl A.T.; Brodie, Nicolas I.; Popov, Konstantin I.; Gudavicius, Geoff; Nelson, Christoph J.; Petrochenko, Evgeniy V.; Dokholyan, Nikolay V.; Borchers, Christoph H. (Journal of Proteomics, 2020)
    For disordered proteins, ligand binding can be a critical event that changes their structural dynamics. The ability to characterize such changes would facilitate the development of drugs designed to stabilize disordered ...