Carrageenans are sulfated polysaccharides found in the cell walls of red algae with 20 – 30 % of the dry weight coming from sulfate esters. The understanding of how heterotrophic bacteria desulfate and depolymerize carrageenan ...

The role that signaling molecules play during morphogenesis and their interactions is a field of intense study and the sea urchin represents a facile system to study these aspects of development in the early embryo. In ...

Secretion is a fundamental process of bacterial microorganisms. It is responsible for diverse functions such as cell-to-cell communication, nutritional up-take, environmental adaptation, physiological responses, and ...

Although its highly infectious nature has led to its classification as a potential bio-terror threat, very little is known about the pathogenesis of Francisella. A complete understanding of the mechanisms employed by ...

This thesis describes work done with the thyroid hormone receptor (TR), a nuclear protein which binds to specific DNA sequences and regulates transcription in response to thyroid hormone levels. The studies can be divided ...

F. tularensis is a Gram-negative bacterial pathogen and it is the causative agent of tularemia. It has the ability to replicate to high numbers within a variety of host cells, including macrophages. Little is known of its ...

Francisella tularensis is a highly virulent, intracellular pathogen that causes the disease tularaemia. Francisella species contain a cluster of genes referred to as the Francisella pathogenicity island (FPI). Several ...

ARS2 is a member of the nuclear cap-binding complex (CBC) that is critical for a number of RNA processing pathways. The emerging model is that ARS2 acts as a master regulator of RNAPII transcript maturation by bringing ...