Supermolecule-assisted imaging of low-molecularweight quaternary-ammonium compounds by MALDI-MS of their non-covalent complexes with cucurbit[7]uril

Date

2020

Authors

Chen, Di
Han, Jun
Yang, Juncong
Schibli, David
Zhang, Zhenzhong
Borchers, Christoph H.

Journal Title

Journal ISSN

Volume Title

Publisher

RSC Advances

Abstract

Cucurbit[7]uril was used to form non-covalent complexes with low-molecular-weight quaternary-ammonium compounds for their indirect analysis by MALDI-MS. By shifting the ion signals to a higher and interference-free mass region, the distributions of neurine, choline, and phosphocholine in rat brain were visualized by MALDI imaging with high selectivity and good sensitivity.

Description

Keywords

Citation

Chen, D., Han, J., Yang, J., Schibli, D., Zhang, Z., & Borchers, C. H. (2020). Supermolecule-assisted imaging of low-molecularweight quaternary-ammonium compounds by MALDI-MS of their non-covalent complexes with cucurbit[7]uril. RSC Advances, 10(56), 34261-34265. https://doi.org/10.1039/d0ra04604c