Engineering knowledge exchange for translational research informatics

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dc.contributor.author Mason-Blakley, F.
dc.date.accessioned 2010-12-21T20:02:10Z
dc.date.available 2010-12-21T20:02:10Z
dc.date.copyright 2010 en
dc.date.issued 2010-12-21T20:02:10Z
dc.identifier.uri http://hdl.handle.net/1828/3176
dc.description.abstract Engineering effective knowledge exchange pathways between scientists and clinicians will accelerate the development and improvement of clinical treatments extracted from lab bench experiments. Many standards development organizations in the field of translational research informatics have attempted to prescribe mechanisms which would provide these knowledge exchange pathways; however, concrete implementations of these standards and the software structures which support them are still lacking. We have explored key technologies and techniques which may facilitate knowledge exchange through clinical coding, a domain specific version of the more general technique of semantic annotation. During the development process we identified and provided potential solutions to four primary problem areas in engineering software enabled knowledge exchange pathways for translational research: architecture, terminology, validation and interface design. We provide both a technical and practical evaluation of a multicomponent architecture which was conceived as a mechanism for producing knowledge exchange pathways between researchers in the field of cancer informatics; however, the principles and process which we apply to cancer informatics could easily be applied to other areas of clinical informatics. en
dc.language English eng
dc.language.iso en en
dc.rights Available to the World Wide Web en
dc.subject Clinical coding en
dc.subject Interoperability en
dc.subject.lcsh UVic Subject Index::Sciences and Engineering::Applied Sciences::Computer science en
dc.title Engineering knowledge exchange for translational research informatics en
dc.type Thesis en
dc.contributor.supervisor Jahnke, Jens H.
dc.degree.department Dept. of Computer Science en
dc.degree.level Master of Science M.Sc. en

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