Combining protein-based biomaterials with stem cells for spinal cord injury repair

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dc.contributor.author Montgomery, A
dc.contributor.author Agbay, A
dc.contributor.author Edgar, JM
dc.contributor.author Gabers, N
dc.contributor.author Gomez, J
dc.contributor.author Mohtaram, NK
dc.contributor.author King, C
dc.contributor.author Mitchell, A
dc.contributor.author Rajwani, A
dc.contributor.author Rattray, D
dc.contributor.author Robinson, M
dc.contributor.author Shapka, A
dc.contributor.author Sun, L
dc.contributor.author Wong, A
dc.contributor.author Willerth, Stephanie
dc.date.accessioned 2015-06-11T22:20:50Z
dc.date.available 2015-06-11T22:20:50Z
dc.date.copyright 2014 en_US
dc.date.issued 2014
dc.identifier.citation Montgomery A, Agbay A, Edgar JM, Gabers N, Gomez J, Mohtaram NK, et al. Combining protein-based biomaterials with stem cells for spinal cord injury repair. OA Stem Cells 2014 Jan 18;2(1):1. en_US
dc.identifier.uri https://www.oapublishinglondon.com/article/1160#
dc.identifier.uri http://hdl.handle.net/1828/6257
dc.description.abstract Introduction Protein-based biomaterials can be combined with stem cells to develop therapies that aid in the regeneration of injured spinal cords. These approaches use various protein scaffolds to support the survival and differentiation of implanted stem cellderived populations into functional neurons and glial cells with the aim of overcoming the inhibitory scarring that restricts cell regrowth after spinal cord injury. The following review evaluates two key protein-based biomaterials–fibrin and collagen–in combination with both pluripotent and multipotent stem cells as strategies for spinal cord injury repair. Recent studies on the protein network of decellularised extracellular matrix are also highlighted as an exciting area for future work. Conclusion The combination of protein-based biomaterials with stem cells shows significant promise as a strategy for spinal cord injury repair. en_US
dc.language.iso en en_US
dc.publisher OA Publishing London en_US
dc.title Combining protein-based biomaterials with stem cells for spinal cord injury repair en_US
dc.type Article en_US
dc.description.scholarlevel Faculty en_US
dc.description.reviewstatus Reviewed en_US

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