Droplet dispensing in digital microfluidic devices: Assessment of long-term reproducibility

dc.contributor.authorElvira, Katherine S.
dc.contributor.authorLeatherbarrow, Robin
dc.contributor.authorEdel, Joshua
dc.contributor.authordeMello, Andrew
dc.date.accessioned2018-10-16T22:56:40Z
dc.date.available2018-10-16T22:56:40Z
dc.date.copyright2012en_US
dc.date.issued2012
dc.description.abstractWe report an in-depth study of the long-term reproducibility and reliability of droplet dispensing in digital microfluidic devices (DMF). This involved dispensing droplets from a reservoir, measuring the volume of both the droplet and the reservoir droplet and then returning the daughter droplet to the original reservoir. The repetition of this process over the course of several hundred iterations offers, for the first time, a long-term view of droplet dispensing in DMF devices. Results indicate that the ratio between the spacer thickness and the electrode size influences the reliability of droplet dispensing. In addition, when the separation between the plates is large, the volume of the reservoir greatly affects the reproducibility in the volume of the dispensed droplets, creating “reliability regimes.” We conclude that droplet dispensing exhibits superior reliability as interplate device spacing is decreased, and the daughter droplet volume is most consistent when the reservoir volume matches that of the reservoir electrode.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.identifier.citationElvira, K.S., Leatherbarrow, R., Edel, J. & deMello, A. (2012). Droplet dispending in digital microfluidic devices: Assessment of long-term reproducibility. Biomicrofluidics, 6(2), 022003. http://dx.doi.org/10.1063/1.3693592en_US
dc.identifier.urihttp://dx.doi.org/10.1063/1.3693592
dc.identifier.urihttp://hdl.handle.net/1828/10160
dc.language.isoenen_US
dc.publisherBiomicrofluidicsen_US
dc.titleDroplet dispensing in digital microfluidic devices: Assessment of long-term reproducibilityen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Elvira_Katherine_Biomicrofluids_2012.pdf
Size:
2.52 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: