Gordon, Reuven2023-04-272023-04-2720222022-04-08Gordon, R. (2022). Future Prospects for Biomolecular Trapping with Nanostructured Metals. ACS Photonics, 9(4), 1127–1135. https://doi.org/10.1021/acsphotonics.2c00231https://doi.org/10.1021/acsphotonics.2c00231http://hdl.handle.net/1828/14997Optical trapping with nanostructured metals has allowed for label-free tether-free analysis of single proteins (and other biomolecules) and their interactions with detector-limited time resolution and a duration extending to hours. This Perspective will provide a brief historical introduction, discuss recent advances to augment the technique with other approaches, and discuss the potential for improved performance and widescale adoption in a range of applications from biologics and drug discovery to fundamental biophysical studies.enoptical tweezersoptical trappingproteinsbiosensorssingle molecule techniquesplasmonicsPostprintDepartment of Electrical and Computer Engineering