Tang, HaoThomas, Suma S.Wolf, LuiseNatarajan, PalaniKo, Young HoWilson, JamesKim, KimoomBohne, Cornelia2023-01-132023-01-1320202020Tang, H., Thomas, S. S., Wolf, L., Natarajan, P., Ko, Y. H., Wilson, J., . . . Bohne, C. (2020). Nonlinear dependence on Na+ ions for the binding dynamics of cucurbit[6]uril with the trans-1-methyl-4-(4-hydroxystyryl)pyridinium cation. The Journal of Physical Chemistry B, 124(45), 10219-10225. https://doi.org/10.1021/acs.jpcb.0c07554https://doi.org/10.1021/acs.jpcb.0c07554http://hdl.handle.net/1828/14663The binding dynamics of the trans-1-methyl-4-(4-hydroxystyryl)pyridinium cation (HSP+) to cucurbit[6]uril (CB[6]) in the presence of Na+ cations were studied to establish the effect of the relative concentrations of the system’s components (HSP+, CB[6], and Na+) on these dynamics. The formation of the HSP+@CB[6] complex was temporally uncoupled from the photoisomerization of trans-HSP+, while a nonlinear effect of the Na+ cation concentration on the HSP+@CB[6] dynamics was observed. This nonlinearity is a consequence of Na+ having the opposite effect on the association and dissociation rate constants for the HSP+@CB[6] complex, creating a conceptual framework for using such nonlinearities to control multistep reactions in cucurbit[n]uril chemistry.enCationsDissociationKinetic parametersPhotoisomerizationArticle