Weller, Kirk Land2024-08-152024-08-1519871987https://hdl.handle.net/1828/20115Several lines of evidence have suggested that vasopressin present in the central nervous system may influence the development of seizures. Homozygous and heterozygous Brattleboro rats deficient in central vasopressin and Long-Evans control rats were electrically kindled in the anterior neocortex. There were no consistent group differences in afterdischarge threshold, the rate of kindling, or percentage of refractory sessions. However, Brattleboro groups had longer afterdischarge durations prior to generalization.84 pagesAvailable to the World Wide WebThesis