Real-time mass spectrometric analysis of catalytic reaction mechanisms

Simple item page
dc.contributor.authorYunker, Lars Peter Erasmus
dc.contributor.supervisorMcIndoe, J. Scott
dc.date.accessioned2017-05-01T15:03:27Z
dc.date.available2017-05-01T15:03:27Z
dc.date.copyright2017en_US
dc.date.issued2017-05-01
dc.degree.departmentDepartment of Chemistryen_US
dc.degree.levelDoctor of Philosophy Ph.D.en_US
dc.description.abstractMass spectrometry was used to study two disparate transformations: in an applied project, the supposed degradation of perfluorooctanesulfonate (PFOS); and in a fundamental study, the Suzuki-Miyaura (SM) reaction was investigated in detail. The first investigation revealed that published methods to degrade PFOS were ineffectual, with apparent decreases being associated with adsorption onto available surfaces. In the Suzuki-Miyaura reaction, a dynamic series of equilibria were observed, and there is no direct evidence of a single pathway. Instead, there appear to be two mechanisms which are active in different conditions (one fluoride, one aqueous). Studies were initiated into the related SM polycondensation reaction and the hydrolysis of aryltrifluoroborates, the former indicating a step-growth mechanism, and the latter indicating a dynamic series of equilibria which are very sensitive to experimental conditions. Processing and interpretation of mass spectrometric data was a significant part of all of these projects, so a python framework was developed to assist in these tasks and its features are also documented herein.en_US
dc.description.proquestcode0488en_US
dc.description.proquestcode0486en_US
dc.description.proquestemaillarsy@uvic.caen_US
dc.description.scholarlevelGraduateen_US
dc.identifier.urihttp://hdl.handle.net/1828/8029
dc.languageEnglisheng
dc.language.isoenen_US
dc.rightsAvailable to the World Wide Weben_US
dc.subjectMass spectrometryen_US
dc.subjectSuzuki-Miyauraen_US
dc.subjectonline reaction monitoringen_US
dc.subjectelectrospray ionizationen_US
dc.subjectESI-MSen_US
dc.subjectperfluorooctane sulfonateen_US
dc.subjectPFOSen_US
dc.subjecttransmetallation mechanismen_US
dc.subjecttrifluoroborate hydrolysisen_US
dc.subjectsuzuki polycondensationen_US
dc.subjectpythonen_US
dc.subjectMSPTen_US
dc.subjectpressurized sample infusionen_US
dc.titleReal-time mass spectrometric analysis of catalytic reaction mechanismsen_US
dc.typeThesisen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Yunker_Lars_PhD_2017.pdf
Size:
38.1 MB
Format:
Adobe Portable Document Format
Description:
complete dissertation
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.74 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Electronic Theses and Dissertations (ETD)
Theses (Chemistry)
 
University of Victoria Libraries

We acknowledge and respect the Lək̓ʷəŋən (Songhees and Esquimalt) Peoples on whose territory the university stands, and the Lək̓ʷəŋən and W̱SÁNEĆ Peoples whose historical relationships with the land continue to this day.