Extremely Fast P – C Bond Formation Using Ruthenium

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dc.contributor.authorKellinghusen, Alexis
dc.date.accessioned2022-06-29T18:00:45Z
dc.date.available2022-06-29T18:00:45Z
dc.date.copyright2022en_US
dc.date.issued2022-06-29
dc.description.abstractThis project is part of ongoing research of a Cp*Ru hydrophosphination catalyst, Ru(5-Cp*)(PPh2)(PPh2H)2, in the Rosenberg group. This catalyst performs rapid regioselective hydrophosphination producing product phosphines in an atom economic process. The previously studied indenyl Ru catalyst had a turnover frequency (TOF) of 7 h-1 (at 90% conversion), whereas this new Cp*Ru catalyst has a TOF of 250 h-1 (at 90% conversion). Objectives of this project included exploring the phosphine and alkene scope involved in catalysis, the catalyst resting state and determining catalytic activity. The Cp*Ru catalyst was generated successfully with phosphines: PTolp2H, PEt2H and PCy2H. Only phosphines with sufficiently acidic P-H groups participated in catalysis due to the proposed turnover limiting step of the mechanism involving an intramolecular proton transfer step. Different alkenes were tested for participation in catalysis; only activated alkenes were found to participate. Understanding the substrate scope and catalyst resting state provides valuable insight and further evidence to support the proposed mechanism which is central for future catalyst design.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelUndergraduateen_US
dc.description.sponsorshipJamie Cassels Undergraduate Research Awards (JCURA)en_US
dc.identifier.urihttp://hdl.handle.net/1828/14018
dc.language.isoenen_US
dc.subjectchemistryen_US
dc.subjectrutheniumen_US
dc.subjectcatalysten_US
dc.subjectcatalysisen_US
dc.subjecthydrophosphinationen_US
dc.subjectphosphorusen_US
dc.subjectcarbonen_US
dc.subjectsubstrate scopeen_US
dc.subjectmechanismen_US
dc.titleExtremely Fast P – C Bond Formation Using Rutheniumen_US
dc.typePosteren_US

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