Benchmarking a new three-dimensional ultrasound system for prostate image guided radiation therapy

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dc.contributor.authorJohnston, Holly A.
dc.contributor.supervisorHilts, Michelle
dc.contributor.supervisorJirasek, Andrew
dc.date.accessioned2008-04-23T19:16:35Z
dc.date.available2008-04-23T19:16:35Z
dc.date.copyright2008en_US
dc.date.issued2008-04-23T19:16:35Z
dc.degree.departmentDepartment of Physics and Astronomy
dc.degree.levelMaster of Science M.Sc.en_US
dc.description.abstractImage guided radiation therapy (IGRT) is a new type of radiotherapy used to deliver lethal doses of radiation to mobile tumors, while preventing surrounding healthy structures from receiving high doses of radiation. It relies on image guidance to track the tumor and ensure its prescribed position in the radiation beam. The main goal of this work was to determine if a new three-dimensional ultrasound (3D US) image guidance device, called the Restitu System, could safely replace (or be used interchangeably with) an existing method involving x-ray images of implanted fiducial markers (FMs) for prostate IGRT. Using comparison statistics called 95 % limits of agreement (LOA), it was found that the new 3D US system did not produce measurements that agreed sufficiently closely to those made using the FM technique, and therefore, could not safely replace FMs for prostate IGRT. Ultrasound image quality and user variability were determined to have a significant impact on the agreement between the two methods. It was further shown that using the Restitu System offered no significant clinical advantages over a conventional patient re-positioning technique.en_US
dc.identifier.urihttp://hdl.handle.net/1828/889
dc.languageEnglisheng
dc.language.isoenen_US
dc.rightsAvailable to the World Wide Weben_US
dc.subjectRadiation Therapyen_US
dc.subjectProstate Canceren_US
dc.subjectUltrasounden_US
dc.subjectImage Guidanceen_US
dc.subject.lcshUVic Subject Index::Sciences and Engineering::Health Sciences::Radiologyen_US
dc.subject.lcshUVic Subject Index::Sciences and Engineering::Physics::Radiationen_US
dc.titleBenchmarking a new three-dimensional ultrasound system for prostate image guided radiation therapyen_US
dc.typeThesisen_US

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