Assignment of Atlantic salmon (Salmo salar) linkage groups to specific chromosomes : conservation of large syntenic blocks corresponding to whole chromosome arms in rainbow trout (Oncorhynchus mykiss)

Simple item page
dc.contributor.authorPhillips, Ruth B.
dc.contributor.authorKeatley, Kimberly A.
dc.contributor.authorMorasch, Matthew R.
dc.contributor.authorVentura, Abigail B.
dc.contributor.authorLubieniecki, Krzysztof P.
dc.contributor.authorKoop, Benjamin F.
dc.contributor.authorDanzmann, Roy G.
dc.contributor.authorDavidson, William S.
dc.date.accessioned2014-08-07T20:45:58Z
dc.date.available2014-08-07T20:45:58Z
dc.date.copyright2009en_US
dc.date.issued2009-08-18
dc.descriptionBioMed Centralen_US
dc.description.abstractBackground: Most teleost species, especially freshwater groups such as the Esocidae which are the closest relatives of salmonids, have a karyotype comprising 25 pairs of acrocentric chromosomes and 48– 52 chromosome arms. After the common ancestor of salmonids underwent a whole genome duplication, its karyotype would have 100 chromosome arms, and this is reflected in the modal range of 96–104 seen in extant salmonids (e.g., rainbow trout). The Atlantic salmon is an exception among the salmonids as it has 72–74 chromosome arms and its karyotype includes 12 pairs of large acrocentric chromosomes, which appear to be the result of tandem fusions. The purpose of this study was to integrate the Atlantic salmon's linkage map and karyotype and to compare the chromosome map with that of rainbow trout. Results: The Atlantic salmon genetic linkage groups were assigned to specific chromosomes in the European subspecies using fluorescence in situ hybridization with BAC probes containing genetic markers mapped to each linkage group. The genetic linkage groups were larger for metacentric chromosomes compared to acrocentric chromosomes of similar size. Comparison of the Atlantic salmon chromosome map with that of rainbow trout provides strong evidence for conservation of large syntenic blocks in these species, corresponding to entire chromosome arms in the rainbow trout. Conclusion: It had been suggested that some of the large acrocentric chromosomes in Atlantic salmon are the result of tandem fusions, and that the small blocks of repetitive DNA in the middle of the arms represent the sites of chromosome fusions. The finding that the chromosomal regions on either side of the blocks of repetitive DNA within the larger acrocentric chromosomes correspond to different rainbow trout chromosome arms provides support for this hypothesis.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipThis project was supported by National Research Initiative Grant no. 2006-04814 from the United States Department of Agriculture (RBP) and funding from Genome Canada and Genome BC (WSD and BFK) and the Natural Sciences and Engineering Research Council of Canada (RGD).en_US
dc.identifier.citationPhillips et al. Assignment of Atlantic salmon (Salmo salar) linkage groups to specific chromosomes: conservation of large syntenic blocks corresponding to whole chromosome arms in rainbow trout (Oncorhynchus mykiss). BMC Genetics 2009, 10:46en_US
dc.identifier.urihttp://www.biomedcentral.com/1471-2156/10/46
dc.identifier.urihttp://dx.doi.org/10.1186/1471-2156-10-46
dc.identifier.urihttp://hdl.handle.net/1828/5522
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.titleAssignment of Atlantic salmon (Salmo salar) linkage groups to specific chromosomes : conservation of large syntenic blocks corresponding to whole chromosome arms in rainbow trout (Oncorhynchus mykiss)en_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Phillips_RuthB_BMCGenet_2009.pdf
Size:
901.43 KB
Format:
Adobe Portable Document Format
Description:
Phillips_RuthB_BMCGenet_2009.pdf
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.74 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Faculty Publications (BioMed Central & Faculty of Science)
 
University of Victoria Libraries

We acknowledge and respect the Lək̓ʷəŋən (Songhees and Esquimalt) Peoples on whose territory the university stands, and the Lək̓ʷəŋən and W̱SÁNEĆ Peoples whose historical relationships with the land continue to this day.