Frequency and intensity of physical activity are associated with insulin resistance in First Nations children and adolescents in 2 remote villages in northern British Columbia, Canada




Mitchell, Marc S.

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Objective: To explore the association of insulin resistance (IR) with direct measures of physical activity (PA). Research methods and procedures: A school-based, cross-sectional study was conducted in two remote British Columbia coastal First Nations villages. 74 healthy boys and girls (mean = 11.8yrs ± 2.2; range = 8.8-18.5yrs) volunteered to participate. PA was measured with the ActiGraph accelerometer. IR was determined using the homeostasis model assessment of insulin resistance (HOMA-IR). Body mass index standardized for age and sex (zBMI) and waist circumference were used to assess total and central adiposity. Results: From the 39 participants with complete data sets, moderate to vigorous intensity physical activity (MVPA) was inversely related to HOMA-IR (r = -.45, p<0.01) while total and central adiposity were directly related (r= .44, p<.01 and r=.35, p<.05, respectively). Discussion: These data provide evidence of the important role of PA, particularly MVPA, in improving IR and potentially preventing type 2 diabetes in First Nations youth.



First Nations, Insulin Resistance, Type 2 Diabetes, Physical Activity, Youth