Kindling with stimulation of the dorsal and ventral striatum

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dc.contributor.authorSaucier, Deborahen_US
dc.date.accessioned2024-08-15T18:19:11Z
dc.date.available2024-08-15T18:19:11Z
dc.date.copyright1990en_US
dc.date.issued1990
dc.degree.departmentDepartment of Psychology
dc.degree.levelMaster of Science M.Sc.en
dc.description.abstractThe characteristics of the kindling of seizures produced by electrical stimulation of the nucleus accumbens (ventral striatum) or of the head, middle region, or tail of the caudate-putamen (dorsal striatum) were investigated in rats. Kindling in the accumbens group was characterized by high thresholds for afterdischarge (AD), forced movements during stimulation, slow progression from nonconvulsive to convulsive seizures, and large increases in the duration of the behavioral seizures. Kindling in the caudate groups was characterized by high AD thresholds, forced movements during stimulation, rapid progression from nonconvulsive to convulsive seizures, and small increases in the duration of the behavioral seizures. The similarities of striatal kindling to limbic and neocortical kindling are discussed, as are the relations of the present findings to previous evidence of striatal involvement in seizures.
dc.format.extent85 pages
dc.identifier.urihttps://hdl.handle.net/1828/19578
dc.rightsAvailable to the World Wide Weben_US
dc.titleKindling with stimulation of the dorsal and ventral striatumen_US
dc.typeThesisen_US

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