Mediated and moderated associations between cumulative lifetime stressor exposure, emotional dysregulation, impulsivity, and lifetime alcohol use: A cross-sectional scoping study of UK drinkers
| dc.contributor.author | Clay, James M. | |
| dc.contributor.author | Baker, Kiera A. | |
| dc.contributor.author | Mezabrovschi, Roxana D. | |
| dc.contributor.author | Berti, Giacomo | |
| dc.contributor.author | Shields, Grant S. | |
| dc.contributor.author | Slavich, George M. | |
| dc.contributor.author | Stafford, Lorenzo D. | |
| dc.contributor.author | Parker, Matthew O. | |
| dc.date.accessioned | 2023-11-30T17:41:42Z | |
| dc.date.available | 2023-11-30T17:41:42Z | |
| dc.date.copyright | 2023 | en_US |
| dc.date.issued | 2023 | |
| dc.description | The authors would like to thank all of the participants who completed the survey. | en_US |
| dc.description.abstract | Stress, trait impulsivity, and emotional dysregulation are independent predictors of alcohol use and misuse, but little is known about the potential mechanisms that link these risk factors together. To address this issue, we carried out an exploratory cross-sectional study, on UK-based participants. Our preregistered, hypothesised theoretical framework was that emotional dysregulation mediates the association between cumulative lifetime stressor exposure and lifetime alcohol use. We also hypothesised that heightened impulsivity would strengthen these relations. As hypothesised, emotional dysregulation fully mediated the relation between cumulative lifetime stressor exposure and lifetime alcohol use. Several facets of impulsivity moderated these associations. For example, as levels of negative urgency increased, the associations between cumulative lifetime stressor exposure and emotional dysregulation, emotional dysregulation and lifetime alcohol use, and lifetime stress exposure and lifetime alcohol use, via emotional dysregulation, strengthened. These preliminary findings propose a theoretically framed model which integrates several prominent risk-factors for alcohol misuse, extending prior research and generating interesting and novel lines of enquiry for longitudinal and cross-cultural analyses. The findings also highlight the potential clinical utility of screening for lifetime stress exposure while tailoring personalised treatment interventions. | en_US |
| dc.description.reviewstatus | Reviewed | en_US |
| dc.description.scholarlevel | Faculty | en_US |
| dc.description.sponsorship | This study was supported by an ESRC Doctoral Training Partnership grant (ES/P000673/1) awarded to J.M.C. and funding from the School of Pharmacy and Biomedical Sciences at the University of Portsmouth made available to K.A.B., R.D.M. and M.O.P. In turn, G.M.S. was supported by grant #OPR21101 from the California Governor’s Office of Planning and Research/California Initiative to Advance Precision Medicine. These funders had no role in study design, data analysis, data interpretation, writing of the report, or the decision to submit for publication. | en_US |
| dc.identifier.citation | Clay, J. M., Baker, K. A., Mezabrovschi, R. D., Berti, G., Shields, G. S., Slavish, G. M., Stafford, L. D., & Parker, M. O. (2023). Mediated and moderated associations between cumulative lifetime stressor exposure, emotional dysregulation, impulsivity, and lifetime alcohol use: A cross-sectional scoping study of UK drinkers. Journal of Psychiatric Research, 164, 140-149. https://doi.org/10.1016/j.jpsychires.2023.06.020 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.jpsychires.2023.06.020 | |
| dc.identifier.uri | http://hdl.handle.net/1828/15663 | |
| dc.language.iso | en | en_US |
| dc.publisher | Journal of Psychiatric Research | en_US |
| dc.subject | Stress | en_US |
| dc.subject | Alcohol | en_US |
| dc.subject | Impulsivity | en_US |
| dc.subject | Risk-taking | en_US |
| dc.subject | Addiction | en_US |
| dc.title | Mediated and moderated associations between cumulative lifetime stressor exposure, emotional dysregulation, impulsivity, and lifetime alcohol use: A cross-sectional scoping study of UK drinkers | en_US |
| dc.type | Article | en_US |