Background correction for DNA array data using a mixture model

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dc.contributor.authorChang, Shan
dc.contributor.supervisorLesperance, M. L.
dc.date.accessioned2010-04-12T16:31:08Z
dc.date.available2010-04-12T16:31:08Z
dc.date.copyright2006en
dc.date.issued2010-04-12T16:31:08Z
dc.degree.departmentDept. of Mathematics and Statisticsen
dc.degree.levelMaster of Science M.Sc.en
dc.description.abstractThere are various kinds of noise that affects DNA array data and it is a challenge to obtain high quality data from an experiment. Background correction is a first step for DNA array data processing; however, current methods for background correction have disadvantages. In this thesis, I propose a mixture model to facilitate the background correction for DNA array data generated by ImaGene. The corresponding software is also provided.en
dc.identifier.urihttp://hdl.handle.net/1828/2550
dc.languageEnglisheng
dc.language.isoenen
dc.rightsAvailable to the World Wide Weben
dc.subjectDNAen
dc.subjectArrayen
dc.subject.lcshUVic Subject Index::Sciences and Engineering::Mathematicsen
dc.titleBackground correction for DNA array data using a mixture modelen
dc.typeThesisen

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