Spectroscopic Analysis to Distinguish Two Cucurbitur[n]urils In a Mixture
| dc.contributor.author | Amini, Darius | |
| dc.date.accessioned | 2022-09-08T16:37:33Z | |
| dc.date.available | 2022-09-08T16:37:33Z | |
| dc.date.copyright | 2022 | en_US |
| dc.date.issued | 2022-09-08 | |
| dc.description.abstract | My research involves cucurbit[n]urils with the objective of distinguishing between CB[6] and CB[7] using fluorescence spectroscopy, and finding the minimum concentration of CB[6] that can be detected in the presence of CB[7]. The objectives also include finding out if the total concentration of CB affects the fluorescence detected using a fluorimeter. When IMA was encapsulated by CB[6] the host-guest complex emitted fluorescence, but this did not occur when CB[7] encapsulated 4-(1H-Imidazol-1-yl)aniline (IMA), as the complex emitted no fluorescence. As 1,6-hexanediamine dihydrochloride (DAH) was added to the CB[6] host-guest complex, IMA was displaced from the complex and fluorescence decreased from the maximum. Overall, through these experiments, CB[6] was found to interfere with the detection of CB[7], but CB[7] does not interfere with the detection of CB[6] because it either forms a non-emissive complex or forms an unstable complex with a low equilibrium constant. Additionally, CB[6] was detected as low as 0.1% to 99.9% ratio of CB[6] to CB[7]. This research is important because host-guest inclusion complexes can be used in real-life applications such as drug delivery and in the future more steps can be taken to deepen the understanding of cucurbit[n]urils complexes and their selectivity. | en_US |
| dc.description.reviewstatus | Reviewed | en_US |
| dc.description.scholarlevel | Undergraduate | en_US |
| dc.description.sponsorship | Valerie Kuehne Undergraduate Research Awards (VKURA) | en_US |
| dc.identifier.uri | http://hdl.handle.net/1828/14225 | |
| dc.language.iso | en | en_US |
| dc.subject | Fluorescence | |
| dc.subject | cucurbit[n]urils | |
| dc.subject | titration | |
| dc.subject | host-guest | |
| dc.subject | Valerie Kuehne Undergraduate Research Awards (VKURA) | |
| dc.subject.department | Department of Chemistry | |
| dc.title | Spectroscopic Analysis to Distinguish Two Cucurbitur[n]urils In a Mixture | en_US |
| dc.type | Poster | en_US |