Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis
| dc.contributor.author | Doyle, Carla M. | |
| dc.contributor.author | Maheu‑Giroux, Mathieu | |
| dc.contributor.author | Lambert, Gilles | |
| dc.contributor.author | Mishra, Sharmistha | |
| dc.contributor.author | Apelian, Herak | |
| dc.contributor.author | Messier‑Peet, Marc | |
| dc.contributor.author | Otis, Joanne | |
| dc.contributor.author | Grace, Daniel | |
| dc.contributor.author | Hart, Trevor A. | |
| dc.contributor.author | Moore, David M. | |
| dc.contributor.author | Lachowsky, Nathan J. | |
| dc.contributor.author | Cox, Joseph | |
| dc.contributor.author | Engage Study Team | |
| dc.date.accessioned | 2022-04-01T15:47:08Z | |
| dc.date.available | 2022-04-01T15:47:08Z | |
| dc.date.copyright | 2020 | en_US |
| dc.date.issued | 2021 | |
| dc.description | The authors would like to thank the Engage study participants, office staff, and community engagement committee members, as well as our community partner agencies REZO, ACCM and Maison Plein Coeur. The authors also wish to acknowledge the support of Jody Jollimore and their contribution(s) to the work presented here. Engage/Momentum II is funded by the Canadian Institutes for Health Research (CIHR, #TE2-138299), the CIHR Canadian HIV/AIDS Trials Network (#CTN300), the Canadian Foundation for AIDS Research (CANFAR, #Engage), the Ontario HIV Treatment Network (OHTN, #1051), the Public Health Agency of Canada (Ref: 4500370314), Canadian Blood Services (#MSM2017LP-OD), and the Ministère de la Santé et des Services sociaux (MSSS) du Québec. CMD is supported by Engage, Universities Without Walls (UWW) and the Fonds de recherche du Québec—Santé (FRQS). MMG acknowledges funding from the CANFAR, CIHR, and FRQS. Finally, the authors would like to thank the Quebec Population Health Research Network (QPHRN) for its contribution to the financing of this publication. | en_US |
| dc.description.abstract | Pre-exposure prophylaxis (PrEP) became publicly available in Quebec for gay, bisexual and other men who have sex with men (GBM) in 2013. We used baseline data from Engage, a cohort of GBM recruited by respondent-driven sampling, to examine patterns of combination HIV prevention use among Montreal GBM since PrEP became available. Latent class analysis, stratified by HIV status, was used to categorize GBM by self reported use of biomedical and behavioural prevention strategies. Correlates of resulting classes were identified using multinomial logistic regression. Among HIV-negative/ unknown GBM (n = 968), we identified four classes: low use of prevention (32%), condoms (40%), seroadaptive behaviour (21%), and biomedical (including PrEP; 7%). Those using prevention (condoms, seroadaptive behaviour, and biomedical) had a higher number of anal sex partners and were more likely to report a recent sexually transmitted infection diagnosis. GBM using biomedical prevention also had a higher level of formal education. Among GBM living with HIV (n = 200), we identified three classes: mainly antiretroviral treatment (ART) with viral suppression (53%), ART with viral suppression and condoms (19%), and ART with viral suppression and seroadaptive behaviour (18%). Again, the number of anal sex partners was higher among those using condoms and seroadaptive behaviours. Our findings show antiretroviral-based prevention, either alone or in combination with other strategies, is clearly a component of the HIV prevention landscape for GBM in Montreal. Nevertheless, PrEP uptake remains low, and there is a need to promote its availability more widely. | en_US |
| dc.description.reviewstatus | Reviewed | en_US |
| dc.description.scholarlevel | Faculty | en_US |
| dc.description.sponsorship | CMD is supported by doctoral awards from Engage, Universities Without Walls (UWW) and the Fonds de recherche du Québec – Santé (FRQS). Grants from the Canadian Institutes of Health Research (CIHR) Canadian Foundation for AIDS Research to MM-G. Engage is supported by grants from the CIHR, Canadian Foundation for AIDS Research, the Ontario HIV Treatment Network, Ryerson University, and the Ministère de la Santé et des Services sociaux (MSSS) du Québec. SM is supported by a New Investigator Award from CIHR and the Ontario HIV Treatment Network. DG is supported by his Canada Research Chair (CRC) in Sexual and Gender Minority Health. TH is supported by an Applied HIV Research Chair from the Ontario HIV Treatment Network. NJL is supported by a Michael Smith Foundation for Health Research Scholar award (#16863). | en_US |
| dc.identifier.citation | Doyle, C. M., Maheu-Giroux, M., Lambert, G., Mishra, S., Apelian, H., Messier-Peet, M., Otis, J., Grace, D., Hart, T. A., Moore, D. M., Lachowsky, N. J., & Cox, J. (2021). “Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.” AIDS and Behavior, 25, 269-283. DOI: https://doi.org/10.1007/ s10461-020-02965-4 | en_US |
| dc.identifier.uri | https://doi.org/10.1007/s10461-020-02965-4 | |
| dc.identifier.uri | http://hdl.handle.net/1828/13827 | |
| dc.language.iso | en | en_US |
| dc.publisher | AIDS and Behavior | en_US |
| dc.subject | Combination HIV prevention | en_US |
| dc.subject | HIV prevention strategies | en_US |
| dc.subject | Men who have sex with men | en_US |
| dc.subject | Pre-exposure prophylaxis | en_US |
| dc.subject | Latent class analysis | en_US |
| dc.title | Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis | en_US |
| dc.type | Article | en_US |