Canadian network for mood and anxiety treatments 2024 clinical practice guideline for the management of perinatal mood, anxiety and related disorders

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dc.contributor.authorVigod, Simone N.
dc.contributor.authorFrey, Benicio
dc.contributor.authorClark, Crystal T.
dc.contributor.authorGrigoriadis, Sophie
dc.contributor.authorBarker, Lucy C.
dc.contributor.authorBrown, Hilary K.
dc.contributor.authorCharlebois, Jaime
dc.contributor.authorDennis, Cindy Lee
dc.contributor.authorFairbrother, Nichole
dc.contributor.authorGreen, Sheryl
dc.contributor.authorLetourneau, Nicole L.
dc.contributor.authorOberlander, Tim F.
dc.contributor.authorSharma, Verinder
dc.contributor.authorSingla, Daisy R.
dc.contributor.authorStewart, Donna E
dc.contributor.authorTomasi, Patricia
dc.contributor.authorEllington, Brittany D.
dc.contributor.authorFleury, Cathleen
dc.contributor.authorTarasoff, Lesley A.
dc.contributor.authorTomfohr-Madsen, Lianne
dc.contributor.authorDa Costa, Deborah
dc.contributor.authorBeaulieu, Serge
dc.contributor.authorBrietzke, Elisa
dc.contributor.authorKennedy, Sidney H.
dc.contributor.authorLam, Raymond W.
dc.contributor.authorMilev, Roumen V.
dc.contributor.authorParikh, Sagar V.
dc.contributor.authorRavindran, Arun V.
dc.contributor.authorSamaan, Zainab
dc.contributor.authorSchaffer, Ayal
dc.contributor.authorTaylor, Valerie H.
dc.contributor.authorTourjman, Smadar V.
dc.contributor.authorVan Ameringen, Michael
dc.contributor.authorYatham, Lakshmi N.
dc.contributor.authorVan Lieshout, Ryan J.
dc.date.accessioned2026-05-07T17:31:19Z
dc.date.available2026-05-07T17:31:19Z
dc.date.issued2025
dc.description.abstractBackground The Canadian Network for Mood and Anxiety Treatments (CANMAT) publishes clinical practice guidelines for mood and anxiety disorders. This CANMAT guideline aims to provide comprehensive clinical guidance for the pregnancy and postpartum (perinatal) management of mood, anxiety and related disorders. Methods CANMAT convened a core editorial group of interdisciplinary academic clinicians and persons with lived experience (PWLE), and 3 advisory panels of PWLE and perinatal health and perinatal mental health clinicians. We searched for systematic reviews of prevention and treatment interventions for perinatal depressive, bipolar, anxiety, obsessive–compulsive and post-traumatic stress disorders (January 2013–October 2023). We prioritized evidence from reviews of randomized controlled trials (RCTs), except for the perinatal safety of medications where reviews of large high-quality observational studies were prioritized due to the absence of RCT data. Targeted searches for individual studies were conducted when systematic reviews were limited or absent. Recommendations were organized by lines of treatment based on CANMAT-defined levels of evidence quality, supplemented by editorial group consensus to balance efficacy, safety, tolerability and feasibility considerations. Results The guideline covers 10 clinical sections in a question-and-answer format that maps onto the patient care journey: case identification; organization and delivery of care; non-pharmacological (lifestyle, psychosocial, psychological), pharmacological, neuromodulation and complementary and alternative medicine interventions; high-risk clinical situations; and mental health of the father or co-parent. Equity, diversity and inclusion considerations are provided. Conclusions This guideline's detailed evidence-based recommendations provide clinicians with key information to promote the delivery of effective and safe perinatal mental healthcare. It is hoped that the guideline will serve as a valuable tool for clinicians in Canada and around the world to help optimize clinical outcomes in the area of perinatal mental health.
dc.description.reviewstatusReviewed
dc.description.scholarlevelFaculty
dc.description.sponsorshipThe authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This work was supported by Health Canada through the Health Care Policy and Strategies Program through the Health Care Policy and Strategies Program (grant number 2324-HQ-000007). The analyses, conclusions, opinions, and statements expressed herein are solely those of the authors and do not reflect those of the funding or data sources; no endorsement is intended or should be inferred.
dc.identifier.citationVigod, S. N., Frey, B. N., Clark, C. T., Grigoriadis, S., Barker, L. C., Brown, H. K., Charlebois, J., Dennis, C., Fairbrother, N., Green, S. M., Letourneau, N. L., Oberlander, T. F., Sharma, V., Singla, D. R., Stewart, D. E., Tomasi, P., Ellington, B. D., Fleury, C., Tarasoff, L. A., . . . Van Lieshout, R. J. (2025). Canadian Network for Mood and Anxiety Treatments 2024 Clinical Practice Guideline for the Management of Perinatal Mood, Anxiety, and Related Disorders: Guide de pratique 2024 du Canadian Network for Mood and Anxiety Treatments pour le traitement des troubles de l’humeur, des troubles anxieux et des troubles connexes périnatals. The Canadian Journal of Psychiatry, 70(6), 429–489. https://doi.org/10.1177/07067437241303031
dc.identifier.urihttps://doi.org/10.1177/07067437241303031
dc.identifier.urihttps://hdl.handle.net/1828/23848
dc.language.isoen
dc.publisherCanadian Journal of Psychiatry
dc.rightsCC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectclinical practice guidelines
dc.subjectdepression
dc.subjectpostpartum depression
dc.subjectmood disorder
dc.subjectanxiety disorder
dc.subjectobsessive-compulsive disorder
dc.subjectpost-traumatic stress disorder
dc.subjectbipolar disorder
dc.subjectperinatal
dc.subjectpostpartum psychosis
dc.subjectpregnancy
dc.subjectpostpartum period
dc.subjectSexual and Reproductive Health and Rights (SRHR) Aspiration Research Cluster
dc.subject.departmentSchool of Public Health and Social Policy
dc.titleCanadian network for mood and anxiety treatments 2024 clinical practice guideline for the management of perinatal mood, anxiety and related disorders
dc.typeArticle

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