Expectancy-driven modulation of pain intensity and perceived damage in a LEGO paradigm

dc.contributor.authorMastrangelo, Sophia
dc.contributor.supervisorKennedy, David
dc.date.accessioned2025-11-28T21:04:32Z
dc.date.available2025-11-28T21:04:32Z
dc.date.issued2025
dc.degree.departmentSchool of Exercise Science, Physical and Health Education
dc.degree.levelMaster of Science MSc
dc.description.abstractPain is a complex experience influenced by sensory, cognitive, and contextual factors. Misinterpretation of pain as direct evidence of equivocal tissue damage can reinforce fear of movement and hinder patient recovery, making it important to understand how expectations shape pain and harm appraisals. This thesis examined whether expectancy framing alters pain responses to an ecologically valid mechanical threat and whether participants dissociate pain intensity from perceived damage. Sixty healthy adults completed five walking trials across a fixed LEGO board: baseline, unexpected LEGO, expected LEGO, and two randomized cream conditions framed as protective (placebo) or sensitizing (nocebo). After each trial, participants reported immediate and delayed pain and damage ratings (0–10 NRS), while ground-reaction forces and step timing were recorded. Results indicated that pain intensity increased sharply at first LEGO exposure (ΔM = +2.95, ~30% of the NRS scale) and was further amplified by the nocebo frame (ΔM = +1.22). The placebo frame showed no significant effects. Changes in damage ratings were more subtle, diverging from pain intensity. Overall, findings demonstrate that contextual threat amplifies pain intensity more strongly than perceived damage, reinforcing a dissociation between the two and underscoring the importance of expectation in pain appraisal.
dc.description.scholarlevelGraduate
dc.identifier.urihttps://hdl.handle.net/1828/22933
dc.languageEnglisheng
dc.language.isoen
dc.rightsAvailable to the World Wide Web
dc.subjectPain
dc.subjectDamage
dc.subjectPerception
dc.subjectHealth Reasearch
dc.subjectNeuroscience
dc.subjectHealthy Population
dc.subjectExpectation
dc.subjectContext
dc.titleExpectancy-driven modulation of pain intensity and perceived damage in a LEGO paradigm
dc.typeThesis

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