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Faculty Publications (Medical Sciences)

Faculty Publications (Medical Sciences)

 

Articles from BioMed Central Click on this link to see Work published with BioMed Central, Chemistry Central and SpringerOpen by researchers at University of Victoria.

Recent Submissions

  • Corsi, Giorgio; Picard, Katherine; di Castro, Maria Amalia; Garofalo, Stefano; Tucci, Federico; Chece, Giuseppina; del Percio, Claudio; Golia, Maria Teresa; Raspa, Marcello; Scavizzi, Ferdinando; Decoeur, Fanny; Lauro, Clotilde; Rigamonti, Mara; Iannello, Fabio; Ragozzino, Davide Antonio; Russo, Eleonora; Bernardini, Giovanni; Nadjar, Agnès; Tremblay, Marie Eve; Babiloni, Claudio (Glia, 2022)
    Microglia, the brain's resident macrophages, actively contribute to the homeostasis of cerebral parenchyma by sensing neuronal activity and supporting synaptic remodeling and plasticity. While several studies demonstrated ...
  • Henri-Bhargava, Alexandre; Herrmann, Nathan; Ismail, Zahinoor; Collins, Rhonda; Desmarais, Philippe; Goodarzi, Zahra; Iaboni, Andrea; Kirkham, Julia; Massoud, Fadi; Moser, Andrea; Silvius, James; Watt, Jennifer; Seitz, Dallas (Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022-01-31)
    Introduction Cognitive enhancers (ie, cholinesterase inhibitors and memantine) can provide symptomatic benefit for some individuals with dementia; however, there are circumstances in which the risks of continuing treatment ...
  • Han, Jun; Bauer, Kylynda C.; York, Elisa M.; Cirstea, Mihai S.; Radisavljevic, Nina; Petersen, Charisse; Huus, Kelsey E.; Brown, Eric M.; Bozorgmehr, Tahereh; Berdun, Rebeca; Bernier, Louis-Philippe; Lee, Amy H. Y.; Woodward, Sarah E.; Krekhno, Zakhar; Hancock, Robert E. W.; Ayala, Victoria; MacVicar, Brian A.; Finlay, Barton Brett (GLIA, 2022-01-12)
    Fecal-oral contamination promotes malnutrition pathology. Lasting consequences of early life malnutrition include cognitive impairment, but the underlying pathology and influence of gut microbes remain largely unknown. ...
  • Chen, Michael X.; Su, Ho-Hsuan; Shiao, Ching-Ya; Chang, Yu-Ting; Chang, Ming-Chu; Kao, Chih-Chin; Wang, San-Yuan; Shih, His-Chang; Tsai, I-Lin (International Journal of Molecular Sciences, 2021)
    Type 1 autoimmune pancreatitis (AIP) is categorized as an IgG4-related disease (IgG4-RD), where a high concentration of plasma IgG4 is one of the common biomarkers among patients. IgG Fc-glycosylation has been reported ...
  • Kim, Amy; Lalonde, Kathryn; Truesdell, Aaron; Gomes Welter, Priscilla; Brocardo, Patricia S.; Rosenstock, Tatiana R.; Gil-Mohapel, Joana (International Journal of Molecular Sciences, 2021)
    Huntington’s disease (HD) is a neurodegenerative disorder caused by a CAG expansion in the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum and cortex. The first symptoms usually ...
  • Rico-Barrio, Irantzu; Peñasco, Sara; Lekunberri, Leire; Serrano, Maitane; Egaña-Huguet, Jon; Mimenza, Amaia; Soria-Gomez, Edgar; Ramos, Almudena; Buceta, Ianire; Gerrikagoitia, Immaculada; Mendizabal-Zubiaga, Juan; Elezgarai, Izaskun; Puente, Nagore; Grandes, Pedro (Biomedicines, 2021)
    Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers ...
  • Schiariti, Verónica; Simeonsson, Rune J.; Hall, Karen (International Journal of Environmental Research and Public Health, 2021)
    In the early years of life, children’s interactions with the physical and social environmentincluding families, schools and communities—play a defining role in developmental trajectories with long-term implications for ...
  • Lee, Thomas H.; Christie, Brian R.; van Praag, Henriette; Lin, Kangguang; Siu, Parco Ming-Fai; Xu, Aimin; So, Kwok-Fai; Yau, Suk-yu (International Journal of Molecular Sciences, 2021)
    AdipoRon, an adiponectin receptor agonist, elicits similar antidiabetic, anti-atherogenic, and anti-inflammatory effects on mouse models as adiponectin does. Since AdipoRon can cross the blood-brain barrier, its chronic ...
  • Schiariti, Verónica (International Journal of Environmental Research and Public Health, 2021)
  • Martins Melzer, Thayza; Meller Manosso, Luana; Yau, Suk-yu; Gil-Mohapel, Joana; Brocardo, Patricia S. (International Journal of Molecular Sciences, 2021)
    Consuming a balanced, nutritious diet is important for maintaining health, especially as individuals age. Several studies suggest that consuming a diet rich in antioxidants and antiinflammatory components such as those ...
  • Delage, Charlotte Isabelle; Šimončičová, Eva; Tremblay, Marie-Ève (Journal of Pharmacological Sciences, 2021)
    Neurodegenerative diseases and their associated cognitive decline are known to be more prevalent during aging. Recent evidence has uncovered the role of microglia, the immunocompetent cells of the brain, in dysfunctions ...
  • Napoli, Silvana B.; Vitale, María Paula; Cafiero, Pablo J.; Micheletti, María Belén; Bradichansky, Paula Pedernera; Lejarraga, Celina; Urinovsky, Maria Gabriela; Escalante, Anabella; Rodriguez, Estela; Schiariti, Verónica (International Journal of Environmental Research and Public Health, 2021)
    Background: Autism spectrum disorder (ASD) affects the daily functioning of children and their families; however, in Argentina, there are no standardized tools to guide the description, evaluation, and follow-up of ...
  • Penedo, M. A.; Rivera-Baltanás, T.; Pérez-Rodríguez, D.; Allen, J.; Borrajo, A.; Alonso-Crespo, D.; Fernandez-Pereira, C.; Nieto-Araujo, M.; Ramos-García, S.; Barreiro-Villar, C.; Caruncho, H. J.; Olivares, J. M.; Agís-Balboa, R. C. (Brain, Behavior, & Immunity – Health, 2021)
    Dopamine and its 5 receptors, which are grouped into two families (D1-like and D2-like), modulate functions at a systemic level in both the central nervous system and periphery. The central nervous system and the immune ...
  • Arbour, Laura; Melnikov, Vladimir; McIntosh, Sarah; Olsen, Britta; Osborne, Geraldine; Vaktskjold, Arild (International Journal of Circumpolar Health, 2009)
    Objectives. Little is known about the rates of congenital anomalies in the northernmost regions of the world. As in other parts of the world, it is crucial to assess the relative rates and trends of adverse birth outcomes ...
  • Lecours, Cynthia; St-Pierre, Marie-Kim; Picard, Katherine; Bordeleau, Maude; Bourque, Melanie; Awogbindin, Ifeoluwa Oluleke; Benadjal, Amin; González Ibanez, Fernando; Gagnon, Dave; Cantin, Leo; Parent, Martin; Di Paolo, Therese; Tremblay, Marie-Eve (Brain, Behavior, and Immunity, 2020)
    Parkinson’s disease (PD) is the most common neurodegenerative motor disorder. The mechanisms underlying the onset and progression of Levodopa (L-Dopa)-induced dyskinesia (LID) during PD treatment remain elusive. Emerging ...
  • Patten, Anna R.; Gil-Mohapel, Joana; Wortman, Ryan C.; Noonan, Athena; Brocardo, Patricia S.; Christie, Brian R. (Brain Sciences, 2013)
    Fetal alcohol spectrum disorders occur when a mother drinks during pregnancy and can greatly influence synaptic plasticity and cognition in the offspring. In this study we determined whether there are periods during brain ...
  • Samson, Jacopo; Piscopo, Irene; Yampolski, Alex; Nahirney, Patrick; Parpas, Andrea; Aggarwal, Amit; Saleh, Raihan; Drain, Charles Michael (Nanomaterials, 2011)
    Plasmid DNA can be used as a template to yield gold, palladium, silver, and chromium nanoparticles of different sizes based on variations in incubation time at 70 °C with gold phosphine complexes, with the acetates of ...
  • Bene Watts, Simona (2020-08-23)
    Background: Long QT syndrome (LQTS) is a cardiac condition which predisposes individuals to syncope, seizures, and sudden cardiac death. There is a high prevalence of congenital LQTS in a First Nations community in Northern ...
  • Kapplinger, Jamie; Erickson, Anders; Asuri, Sirisha; Tester, David J.; McIntosh, Sarah; Kerr, Charles R.; Morrison, Julie; Tang, Anthony; Sanatani, Shubhayan; Arbour, Laura; Ackerman, Michael J. (Journal of Medical Genetics, 2017)
    Background Variable expressivity and incomplete penetrance between individuals with identical long QT syndrome (LQTS) causative mutations largely remain unexplained. Founder populations provide a unique opportunity to ...
  • Anand, Sonia S.; Abonyi, Sylvia; Arbour, Laura; Balasubramanian, Kumar; Brook, Jeffrey; Castleden, Heather; Chrisjohn, Vicky; Cornelius, Ida; Davis, Albertha Darlene; Desai, Dipika; de Souza, Russell J.; Friedrich, Matthias G.; Harris, Stewart; Irvine, James; L’Hommecourt, Jean; Littlechild, Randy; Mayotte, Lisa; McIntosh, Sarah; Morrison, Julie; Oster, Richard T.; Picard, Manon; Pictou Landing First Nation; Poirier, Paul; Schulze, Karleen M.; Toth, Ellen L. (The Lancet Planet Health, 2019)
    Summary Background Historical, colonial, and racist policies continue to influence the health of Indigenous people, and they continue to have higher rates of chronic diseases and reduced life expectancy compared with ...

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