Probing the Microenvironments in a Polymer-Wrapped Core−Shell Nanoassembly Using Pyrene Chromophores

Date

2018

Authors

Wu, Tuoqi
Oake, Jessy
Liu, Zhongde
Bohne, Cornelia
Branda, Neil R.

Journal Title

Journal ISSN

Volume Title

Publisher

ACS Omega

Abstract

The local environments within an amphiphilic polymer shell wrapped around lanthanide-doped upconverting nanoparticles were probed using steady-state and time-resolved fluorescence spectroscopy techniques. Emission lifetime measurements of pyrene chromophores trapped within the polymer shell reveal that there are at least two environments, where the organic pyrene molecules are encapsulated in hydrophobic environments that have lower polarity than in water. The migration of pyrene chromophores from their initial location to another location was also observed, demonstrating that the polymeric shell provides both hydrophobicity and mobility for entrapped molecules. These results offer insight into what outcomes can be expected when chemical reactions are carried out in these nanoassemblies, especially if they are to be used as nanoreactors for synthesis or delivery vehicles for therapeutics.

Description

Keywords

Fluorescence, Nanoparticles, Nanoreactors, Nanostructures, Polyoxyalkylenes

Citation

Wu, T., Oake, J., Liu, Z., Bohne, C. & Branda, N.R. (2018). Probing the Microenvironments in a Polymer- Wrapped Core-Shell Nanoassemble Using Pyrene Chromophores. ACS Omega, 3(7), 7673-7680. http://dx.doi.org/10.1021/acsomega.8b00953