Silicate-based electro-conductive inks for printing soft electronics and tissue engineering

dc.contributor.authorSamimi Gharaie, Sadaf
dc.contributor.authorSeyfoori, Amir
dc.contributor.authorKhun Jush, Bardia
dc.contributor.authorZhou, Xiong
dc.contributor.authorPagan, Erik
dc.contributor.authorGodau, Brent
dc.contributor.authorAkbari, Mohsen
dc.date.accessioned2022-11-19T16:11:28Z
dc.date.available2022-11-19T16:11:28Z
dc.date.copyright2021en_US
dc.date.issued2021
dc.description.abstractHydrogel-based bio-inks have been extensively used for developing three-dimensional (3D) printed biomaterials for biomedical applications. However, poor mechanical performance and the inability to conduct electricity limit their application as wearable sensors. In this work, we formulate a novel, 3D printable electro-conductive hydrogel consisting of silicate nanosheets (Laponite), graphene oxide, and alginate. The result generated a stretchable, soft, but durable electro-conductive material suitable for utilization as a novel electro-conductive bio-ink for the extrusion printing of different biomedical platforms, including flexible electronics, tissue engineering, and drug delivery. A series of tensile tests were performed on the material, indicating excellent stability under significant stretching and bending without any conductive or mechanical failures. Rheological characterization revealed that the addition of Laponite enhanced the hydrogel’s mechanical properties, including stiffness, shear-thinning, and stretchability. We also illustrate the reproducibility and flexibility of our fabrication process by extrusion printing various patterns with different fiber diameters. Developing an electro-conductive bio-ink with favorable mechanical and electrical properties offers a new platform for advanced tissue engineering.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipThis research was funded by Natural Sciences and Engineering Research Council of Canada (NSERC), the Canadian Institutes of Health Researches (CIHR), and the Canadian Foundation for Innovations (CFI).en_US
dc.identifier.citationSamimi Gharaie, S., Seyfoori, A., Khun Jush, B., Zhou, X., Pagan, E., Godau, B., & Akbari, M. (2021). “Silicate-based electro-conductive inks for printing soft electronics and tissue engineering.” Gels, 7(4), 240. https://doi.org/10.3390/gels7040240en_US
dc.identifier.urihttps://doi.org/10.3390/gels7040240
dc.identifier.urihttp://hdl.handle.net/1828/14510
dc.language.isoenen_US
dc.publisherGelsen_US
dc.subject3D printingen_US
dc.subjectelectrically conductive bio-inken_US
dc.subjectLaponiteen_US
dc.subjectgraphene oxideen_US
dc.titleSilicate-based electro-conductive inks for printing soft electronics and tissue engineeringen_US
dc.typeArticleen_US

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