Review: Capripoxvirus Diseases: Current Status and Opportunities for Control
Date
2017
Authors
Tuppurainen, E.S.M.
Venter, E.H.
Shisler, J.L.
Gari, G.
Mekonnen, G.A.
Juleff, N.
Lyons, N.A.
De Clercq, K.
Upton, Chris
Bowden, T.R.
Journal Title
Journal ISSN
Volume Title
Publisher
Transboundary and Emerging Diseases
Abstract
Lumpy skin disease, sheeppox and goatpox are high-impact diseases of domestic ruminants with a devastating effect on cattle, sheep and goat farming industries in endemic regions. In this article, we review the current geographical distribution, economic impact of an outbreak, epidemiology, transmission and immunity of capripoxvirus. The special focus of the article is to scrutinize the use of currently available vaccines to investigate the resource needs and challenges that will have to be overcome to improve disease control and eradication, and progress on the development of safer and more effective vaccines. In addition, field evaluation of the efficacy of the vaccines and the genomic database available for poxviruses are discussed.
Description
Keywords
lumpy skin disease, sheeppox, goatpox, immunity, control, vaccines
Citation
Tuppurainen, E.S.M.; Venter, E.H.; Shisler, J.L. Gari, G.; Mekonnen, G.A.; Juleff, N.; … & Babiuk, L.A. (2017). Review: Capripoxvirus Diseases: Current Status and Opportunities for Control. Transboundary and Emerging Diseases, 64(3), 729-745. doi: 10.1111/tbed.12444