The genome of Shope fibroma virus, a tumorigenic poxvirus, contains a growth factor gene with sequence similarity to those encoding epidermal growth factor and transforming growth factor alpha

Date

1987

Authors

Chang, Wen
Upton, Chris
Hu, Shiu-Lok
Purchio, A. F.
McFadden, Grant

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

Degenerate oligonucleotide probes corresponding to a highly conserved region common to epidermal growth factor, transforming growth factor alpha, and vaccinia growth factor were used to identify a novel growth factor gene in the Shope fibroma virus genome. Sequence analysis indicates that the Shope fibroma growth factor is a distinct new member of this family of growth factors.

Description

Keywords

Citation

Chang, W. et al. Mol. Cell. Biol. January 1987 vol. 7 no. 1 535-540