A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation

Date

2010

Authors

Stanley, C.E.
Elvira, K.S.
Niu, X.N.
Gee, A.D.
Ces, O.
Edel, J.B.
deMello, A.J.

Journal Title

Journal ISSN

Volume Title

Publisher

Chemical Communications

Abstract

We present a simple, automated method for high-throughput formation of droplet interface bilayers (DIBs) in a microfluidic device. We can form complex DIB networks that are able to fill predefined three dimensional architectures. Moreover, we demonstrate the flexibility of the system by using a variety of lipids including 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).

Description

Keywords

Citation

Stanley, C.E., Elvira, K.S., Niu, X.Z., Gee, A.D., Ces, O., Edel, J.B. & deMello, A.J. (2010). A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation. Chemical Communications, 46(10), 1620-1622. https://doi.org/10.1039/B924897H