Cell Therapy for Spinal Cord Regeneration

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dc.contributor.authorWillerth, Stephanie
dc.contributor.authorSakiyama-Elbert, Shelly E
dc.date.accessioned2015-07-06T17:56:02Z
dc.date.available2015-07-06T17:56:02Z
dc.date.copyright2007en_US
dc.date.issued2007-10-05
dc.descriptionPost peer review (post print)en_US
dc.description.abstractThis review presents a summary of the various types of cellular therapy used to treat spinal cord injury. The inhibitory environment and loss of axonal connections after spinal cord injury pose many obstacles to regenerating the lost tissue. Cellular therapy provides a means of restoring the cells lost to the injury and could potentially promote functional recovery after such injuries. A wide range of cell types have been investigated for such uses and the advantages and disadvantages of each cell type are discussed along with the research studying each cell type. Additionally, methods of delivering cells to the injury site are evaluated. Based on the current research, suggestions are given for future investigation of cellular therapies for spinal cord regeneration.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipFinancial support for this work was provided by NIH R01 NS051454.en_US
dc.identifier.citationWillerth, S.M. and S.E. Sakiyama-Elbert (2008) Cell therapy for spinal cord regeneration. Adv Drug Deliv Rev .60(2): 263–276en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/pii/S0169409X07002487
dc.identifier.urihttp://dx.doi.org/10.1016/j.addr.2007.08.028
dc.identifier.urihttp://hdl.handle.net/1828/6289
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectembryonic stem cells
dc.subjectneural stem cells
dc.subjectspinal cord injury
dc.subjectregenerative medicine
dc.subjectbone marrow stromal cells
dc.subjectbiomaterials
dc.subject.departmentDepartment of Mechanical Engineering
dc.subject.departmentSchool of Medical Sciences
dc.titleCell Therapy for Spinal Cord Regenerationen_US
dc.typePreprinten_US

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