The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps
Date
2016
Authors
Gottlieb, Sami L.
Deal, Carolyn D.
Giersing, Birgitte
Rees, Helen
Boland, Gail
Johnston, Christine
Timms, Peter
Gray-Owen, Scott D.
Jerse, Ann E.
Cameron, Caroline E.
Journal Title
Journal ISSN
Volume Title
Publisher
Vaccine
Abstract
In 2014, the World Health Organization, the US National Institutes of Health, and global technical partners published a comprehensive roadmap for development of new vaccines against sexually transmitted infections (STIs). Since its publication, progress has been made in several roadmap activities: obtaining better epidemiologic data to establish the public health rationale for STI vaccines, modeling the theoretical impact of future vaccines, advancing basic science research, defining preferred product characteristics for first-generation vaccines, and encouraging investment in STI vaccine development. This article reviews these overarching roadmap activities, provides updates on research and development of individual vaccines against herpes simplex virus, Chlamydia trachomatis, Neisseria gonorrhoeae, and Treponema pallidum, and discusses important next steps to advance the global roadmap for STI vaccine development.
Description
The findings and conclusions of this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
Keywords
Sexually transmitted infections, Vaccines, STI vaccine development, Roadmap
Citation
Gottlieb, S.L., Deal, C.D., Giersing, B., Rees, H., Boland, G., Johnston, C., … Broute, N. (2016). The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps. Vaccine, 34, 2939- 2947. http://dx.doi.org/10.1016/j.vaccine.2016.03.111