Priorities for sexually transmitted infection vaccine research and development: Results from a survey of global leaders and representatives

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dc.contributor.authorPlotnikoff, Kara M.
dc.contributor.authorDonken, Robine
dc.contributor.authorSmith, Laurie
dc.contributor.authorCameron, Caroline E.
dc.contributor.authorLaMontagne, D. Scott
dc.contributor.authorBettinger, Julie A.
dc.contributor.authorSadarangani, Manish
dc.contributor.authorGrennan, Troy
dc.contributor.authorRacey, C. Sarai
dc.contributor.authorHybiske, Kevin
dc.contributor.authorNaus, Monika
dc.contributor.authorMonteiro, Amanda
dc.contributor.authorOgilvie, Gina S.
dc.date.accessioned2021-07-13T13:33:45Z
dc.date.available2021-07-13T13:33:45Z
dc.date.copyright2021en_US
dc.date.issued2021
dc.description.abstractObjective: To determine the sexually transmitted infection (STI) vaccine research priorities of global leaders in STI vaccine research, development, and service provision. Methods: Global representatives attending the STI Vaccines: Opportunities for Research, Development, and Implementation symposium preceding the STI & HIV World Congress in 2019 were invited to complete an electronic survey. We asked participants to rank by importance/priority for STI vaccine development the following areas of focus: specific STIs (gonorrhea, chlamydia, syphilis, herpes, and trichomoniasis), broad research domains (basic science, funding, communication, program planning, and vaccine hesitancy), and specific research activities related to these domains. We calculated weighted value scores based on the 3 ranking (e.g., first, second, third) and the total number of responses in order to produce a ranked list of the priorities. Results: A total of 46 out of 97 (44%) symposium attendees responded to the survey. Gonorrhea was identified as the STI that should be prioritized for vaccine development, followed by syphilis with weighted value scores of 3.82 and 3.37, respectively, out of a maximum of five. Basic science (and vaccine development) was the domain ranked with the highest priority with a weighted value score of 4.78 out of six. Research activities related to basic science and vaccine development (including pre-clinical and clinical trials, and surveillance measures) and increased funding opportunities were the most highly ranked activities in the “STI vaccine development” and “research domains and activities” categories. Conclusion: Global leaders in attendance at the STI Vaccines symposium prioritized continued scientific work in vaccine development and program planning. Gonorrhea was identified as the highest priority infection, followed by syphilis.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipWe would like to thank the STI & HIV 2019 World Congress for the time and space to host this symposium, and for allowing the survey to be distributed. Additional thanks to the symposium attendees for completing this survey.en_US
dc.identifier.citationPlotnikoff, K. M., Donken, R., Smith, L., Cameron, C., LaMontagne, D. S., Bettinger, J. A., Sadarangani, M., Grennan, T., Racey, C. S., Hybiske, K., Naus, M., Monteiro, A., Ogilvie, G. S. (2021). Priorities for sexually transmitted infection vaccine research and development: Results from a survey of global leaders and representatives. Vaccine: X.en_US
dc.identifier.urihttps://doi.org/10.1016/j.jvacx.2021.100107
dc.identifier.urihttp://hdl.handle.net/1828/13111
dc.language.isoenen_US
dc.publisherVaccine: Xen_US
dc.rightsAttribution-NonCommercial-NoDerivs 2.5 Canada*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/ca/*
dc.subjectsexually transmitted infections
dc.subjectprevention
dc.subjectvaccines
dc.subjectpublic health
dc.subjectpriorities
dc.subject.departmentDepartment of Biochemistry and Microbiology
dc.titlePriorities for sexually transmitted infection vaccine research and development: Results from a survey of global leaders and representativesen_US
dc.typePostprinten_US

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