Multiscale Control of Hierarchical Structure in Crystalline Block Copolymer Nanoparticles Using Microfluidics

Date

2015

Authors

Bains, Aman
Cao, Yimeng
Moffitt, Matthew G.

Journal Title

Journal ISSN

Volume Title

Publisher

Macromolecular Rapid Communications

Abstract

Hierarchical semicrystalline block copolymer nanoparticles are produced in a segmented gas-liquid microfluidic reactor with top-down control of multiscale structural features, including nanoparticle morphologies, sizes, and internal crystallinities. Control of multiscale structure on disparate length scales by a single control variable (flow rate) enables tailoring of drug delivery nanoparticle function including release rates.

Description

Keywords

Block copolymers, self-assembly, drug delivery, microfluidics, Nanoparticles

Citation

Bains, A., Cao, Y., & Moffitt, M. G. (2015). Multiscale Control of Hierarchical Structure in Crystalline Block Copolymer Nanoparticles Using Microfluidics. Macromolecular Rapid Communications, 36(22), 2000-2005. https://doi.org/10.1002/marc.201500359.