Multiscale Control of Hierarchical Structure in Crystalline Block Copolymer Nanoparticles Using Microfluidics
Date
2015
Authors
Bains, Aman
Cao, Yimeng
Moffitt, Matthew G.
Journal Title
Journal ISSN
Volume Title
Publisher
Macromolecular Rapid Communications
Abstract
Hierarchical semicrystalline block copolymer nanoparticles are produced in a segmented gas-liquid microfluidic reactor with top-down control of multiscale structural features, including nanoparticle morphologies, sizes, and internal crystallinities. Control of multiscale structure on disparate length scales by a single control variable (flow rate) enables tailoring of drug delivery nanoparticle function including release rates.
Description
Keywords
Block copolymers, self-assembly, drug delivery, microfluidics, Nanoparticles
Citation
Bains, A., Cao, Y., & Moffitt, M. G. (2015). Multiscale Control of Hierarchical Structure in Crystalline Block Copolymer Nanoparticles Using Microfluidics. Macromolecular Rapid Communications, 36(22), 2000-2005. https://doi.org/10.1002/marc.201500359.