In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function

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dc.contributor.authorMartins Melzer, Thayza
dc.contributor.authorMeller Manosso, Luana
dc.contributor.authorYau, Suk-yu
dc.contributor.authorGil-Mohapel, Joana
dc.contributor.authorBrocardo, Patricia S.
dc.date.accessioned2021-05-18T20:29:15Z
dc.date.available2021-05-18T20:29:15Z
dc.date.copyright2021en_US
dc.date.issued2021
dc.description.abstractConsuming a balanced, nutritious diet is important for maintaining health, especially as individuals age. Several studies suggest that consuming a diet rich in antioxidants and antiinflammatory components such as those found in fruits, nuts, vegetables, and fish may reduce agerelated cognitive decline and the risk of developing various neurodegenerative diseases. Numerous studies have been published over the last decade focusing on nutrition and how this impacts health. The main objective of the current article is to review the data linking the role of diet and nutrition with aging and age-related cognitive decline. Specifically, we discuss the roles of micronutrients and macronutrients and provide an overview of how the gut microbiota-gut-brain axis and nutrition impact brain function in general and cognitive processes in particular during aging. We propose that dietary interventions designed to optimize the levels of macro and micronutrients and maximize the functioning of the microbiota-gut-brain axis can be of therapeutic value for improving cognitive functioning, particularly during aging.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipThis research is funded by the open fund supported by Open Research Fund of State Key Laboratory of Brain and Cognition, University of Hong Kong; and Hong Kong Research Grant Council General Research Fund (15100018) awarded to S.Y. Yau.en_US
dc.identifier.citationMartins Melzer, T., Meller Manosso, L., Yau, S., Gil-Mohapel, J., & Brocardo, P. S. (2021). In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function. International Journal of Molecular Sciences, 22(9), 1-25. https://doi.org/10.3390/ijms22095026.en_US
dc.identifier.urihttps://doi.org/10.3390/ijms22095026
dc.identifier.urihttp://hdl.handle.net/1828/12980
dc.language.isoenen_US
dc.publisherInternational Journal of Molecular Sciencesen_US
dc.subjectaging
dc.subjectcognition
dc.subjectmacronutrients
dc.subjectmicrobiota-gut-brain axis
dc.subjectmicronutrients
dc.subjectneutrodegeneration
dc.subjectnutrition
dc.subjectIsland Medical Program
dc.subject.departmentDivision of Medical Sciences
dc.subject.departmentSchool of Medical Sciences
dc.titleIn Pursuit of Healthy Aging: Effects of Nutrition on Brain Functionen_US
dc.typeArticleen_US

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