Nonlinear dependence on Na+ ions for the binding dynamics of cucurbit[6]uril with trans-1-methyl-4-(4-hydroxystyryl)pyridinium cation

Date

2020

Authors

Tang, Hao
Thomas, Suma S.
Wolf, Luise
Natarajan, Palani
Ko, Young Ho
Wilson, James
Kim, Kimoom
Bohne, Cornelia

Journal Title

Journal ISSN

Volume Title

Publisher

The Journal of Physical Chemistry

Abstract

The binding dynamics of the trans-1-methyl-4-(4-hydroxystyryl)pyridinium cation (HSP+) to cucurbit[6]uril (CB[6]) in the presence of Na+ cations were studied to establish the effect of the relative concentrations of the system’s components (HSP+, CB[6], and Na+) on these dynamics. The formation of the HSP+@CB[6] complex was temporally uncoupled from the photoisomerization of trans-HSP+, while a nonlinear effect of the Na+ cation concentration on the HSP+@CB[6] dynamics was observed. This nonlinearity is a consequence of Na+ having the opposite effect on the association and dissociation rate constants for the HSP+@CB[6] complex, creating a conceptual framework for using such nonlinearities to control multistep reactions in cucurbit[n]uril chemistry.

Description

Keywords

Cations, Dissociation, Kinetic parameters, Photoisomerization

Citation

Tang, H., Thomas, S. S., Wolf, L., Natarajan, P., Ko, Y. H., Wilson, J., . . . Bohne, C. (2020). Nonlinear dependence on Na+ ions for the binding dynamics of cucurbit[6]uril with the trans-1-methyl-4-(4-hydroxystyryl)pyridinium cation. The Journal of Physical Chemistry B, 124(45), 10219-10225. https://doi.org/10.1021/acs.jpcb.0c07554