Development of a Low Bias Method for Characterizing Viral Populations Using Next Generation Sequencing Technology

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Willerth_Stephanie_PLoSONE_2010.pdf (1.44 MB)

Date

2010-10-22

Authors

Willerth, Stephanie
Pedro, HeĢlder A. M.
Pachter, Lior
Humeau, Laurent M
Arkin, Adam P
Schaffer, David V

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Volume Title

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PLoS ONE

Abstract

With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (HIV), and an additional 4.1 million people becoming infected each year, it is important to understand how this virus mutates and develops resistance in order to design successful therapies.

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Citation

Willerth SM, Pedro HAM, Pachter L, Humeau LM, Arkin AP, et al. (2010) Development of a Low Bias Method for Characterizing Viral Populations Using Next Generation Sequencing Technology. PLoS ONE 5(10): e13564. doi: 10.1371/journal.pone.0013564

URI

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013564
 http://dx.doi.org/doi:10.1371/journal.pone.0013564
 http://hdl.handle.net/1828/6284

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Faculty Publications (Engineering and Computer Science)
 
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