Attraction by repulsion: compounds with like charges undergo self-assembly in water that improves in high salt and persists in real biological fluids
Date
2016
Authors
Garnett, Graham A. E.
Daze, Kevin D.
Diaz, Jorge A. Pena
Fagen, Noah
Shaurya, Alok
Ma, Manuel C. F.
Collins, Mary S.
Johnson, Darren W.
Zakharov, Lev N.
Hof, Fraser
Journal Title
Journal ISSN
Volume Title
Publisher
Chemical Communications
Abstract
We report a family of highly anionic calixarenes that form discrete homo-dimeric assemblies in pure water, that get stronger in high salt solutions, and that remain assembled in complex, denaturing solutions like real urine. The results reveal the potential of like-charged subunits for self-assembly in high-salt solutions and biological fluids.
Description
Keywords
Citation
Garnett, G. A. E., Daze, K. D., Diaz, J. A. P., Fagen, N., Shaurya, A., Ma, M. C. F., … Hof, F. (2016). Attraction by repulsion: compounds with like charges undergo self-assembly in water that improves in high salt and persists in real biological fluids. Chemical Communications, 52(13), 2768-2771. https://doi.org/10.1039/c5cc10527g