Recent segmental and gene duplications in the mouse genome

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dc.contributor.authorCheung, Joseph
dc.contributor.authorWilson, Michael D
dc.contributor.authorZhang, Junjun
dc.contributor.authorKhaja, Razi
dc.contributor.authorMacDonald, Jeffrey R
dc.contributor.authorHeng, Henry HQ
dc.contributor.authorKoop, Ben F
dc.contributor.authorScherer, Stephen W
dc.date.accessioned2013-05-08T23:18:59Z
dc.date.available2013-05-08T23:18:59Z
dc.date.copyright2003en_US
dc.date.issued2003-07
dc.descriptionBioMed Centralen_US
dc.description.abstractBackground: The high quality of the mouse genome draft sequence and its ssociated annotations are an invaluable biological resource. Identifying recent duplications in the mouse genome, especially in regions containing genes, may highlight important events in recent murine evolution. In addition, detecting recent sequence duplications can reveal potentially problematic regions of the genome assembly. We use BLAST-based computational heuristics to identify large (≥ 5 kb) and recent (≥ 90% sequence identity) segmental duplications in the mouse genome sequence. Here we present a database of recently duplicated regions of the mouse genome found in the mouse genome sequencing consortium (MGSC) February 2002 and February 2003 assemblies.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.identifier.citationCheung, J., Wilson, M., Zhang, J., Khaja, R., MacDonald, J., Heng, H., . . . Scherer, S. (2003). Recent segmental and gene duplications in the mouse genome. Genome Biology, 4(8), R47. Retrieved from http://genomebiology.com/2003/4/8/R47en_US
dc.identifier.urihttp://hdl.handle.net/1828/4606
dc.identifier.urihttp://genomebiology.com/2003/4/8/R47
dc.language.isoenen_US
dc.publisherGenome Biologyen_US
dc.subjectsequencing
dc.subjectmouse genome
dc.subjectCentre for Biomedical Research
dc.subject.departmentDepartment of Biology
dc.titleRecent segmental and gene duplications in the mouse genomeen_US
dc.typeArticleen_US

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