Future Prospects for Biomolecular Trapping with Nanostructured Metals
Date
2022-04-08
Authors
Gordon, Reuven
Journal Title
Journal ISSN
Volume Title
Publisher
ACS Photonics
Abstract
Optical trapping with nanostructured metals has allowed for label-free tether-free analysis of single proteins (and other biomolecules) and their interactions with detector-limited time resolution and a duration extending to hours. This Perspective will provide a brief historical introduction, discuss recent advances to augment the technique with other approaches, and discuss the potential for improved performance and widescale adoption in a range of applications from biologics and drug discovery to fundamental biophysical studies.
Description
Keywords
optical tweezers, optical trapping, proteins, biosensors, single molecule techniques, plasmonics
Citation
Gordon, R. (2022). Future Prospects for Biomolecular Trapping with Nanostructured Metals. ACS Photonics, 9(4), 1127–1135. https://doi.org/10.1021/acsphotonics.2c00231