Future Prospects for Biomolecular Trapping with Nanostructured Metals

dc.contributor.authorGordon, Reuven
dc.date.accessioned2023-04-27T14:26:19Z
dc.date.available2023-04-27T14:26:19Z
dc.date.copyright2022en_US
dc.date.issued2022-04-08
dc.description.abstractOptical trapping with nanostructured metals has allowed for label-free tether-free analysis of single proteins (and other biomolecules) and their interactions with detector-limited time resolution and a duration extending to hours. This Perspective will provide a brief historical introduction, discuss recent advances to augment the technique with other approaches, and discuss the potential for improved performance and widescale adoption in a range of applications from biologics and drug discovery to fundamental biophysical studies.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipFunding provided by the Human Frontier Science Program (RGP0027/2020-ITZHAKI) and Natural Sciences and Engineering Research Council (RGPIN-2017-03830).en_US
dc.identifier.citationGordon, R. (2022). Future Prospects for Biomolecular Trapping with Nanostructured Metals. ACS Photonics, 9(4), 1127–1135. https://doi.org/10.1021/acsphotonics.2c00231en_US
dc.identifier.urihttps://doi.org/10.1021/acsphotonics.2c00231
dc.identifier.urihttp://hdl.handle.net/1828/14997
dc.language.isoenen_US
dc.publisherACS Photonicsen_US
dc.subjectoptical tweezers
dc.subjectoptical trapping
dc.subjectproteins
dc.subjectbiosensors
dc.subjectsingle molecule techniques
dc.subjectplasmonics
dc.subject.departmentDepartment of Electrical and Computer Engineering
dc.titleFuture Prospects for Biomolecular Trapping with Nanostructured Metalsen_US
dc.typePostprinten_US

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