Smart bioinks for the printing of human tissue models

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dc.contributor.authorMaan, Zeina
dc.contributor.authorMasri, Nadia Z.
dc.contributor.authorWillerth, Stephanie M.
dc.date.accessioned2022-10-27T15:59:24Z
dc.date.available2022-10-27T15:59:24Z
dc.date.copyright2022en_US
dc.date.issued2022
dc.description.abstract3D bioprinting has tremendous potential to revolutionize the field of regenerative medicine by automating the process of tissue engineering. A significant number of new and advanced bioprinting technologies have been developed in recent years, enabling the generation of increasingly accurate models of human tissues both in the healthy and diseased state. Accordingly, this technology has generated a demand for smart bioinks that can enable the rapid and efficient generation of human bioprinted tissues that accurately recapitulate the properties of the same tissue found in vivo. Here, we define smart bioinks as those that provide controlled release of factors in response to stimuli or combine multiple materials to yield novel properties for the bioprinting of human tissues. This perspective piece reviews the existing literature and examines the potential for the incorporation of micro and nanotechnologies into bioinks to enhance their properties. It also discusses avenues for future work in this cutting-edge field.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipThis work was funded by the NSERC Discovery Grant program, the Canadian Institutes for Health Research Project Grant program, Innovate BC’s Ignite program, the Alzheimer’s Association, Canada Research Chairs and the Michael Smith Foundation for Health Research and Pacific Parkinson’s Research Institute’s Innovation to Commercialization grant and Biotalent Canada.en_US
dc.identifier.citationMaan, Z., Masri, N., & Willerth, S. (2022). “Smart bioinks for the printing of human tissue models.” Biomolecules, 12(1), 141. https://doi.org/10.3390/biom12010141en_US
dc.identifier.urihttps://doi.org/10.3390/biom12010141
dc.identifier.urihttp://hdl.handle.net/1828/14320
dc.language.isoenen_US
dc.publisherBiomoleculesen_US
dc.subject3D bioprinting
dc.subjectbiomaterials
dc.subjectsmall molecules
dc.subjectcontrolled release
dc.subjectdrug delivery
dc.subjectstem cells
dc.subjectCentre for Advanced Materials and Related Technology (CAMTEC)
dc.subject.departmentDepartment of Mechanical Engineering
dc.subject.departmentSchool of Medical Sciences
dc.titleSmart bioinks for the printing of human tissue modelsen_US
dc.typeArticleen_US

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