Growth of tumor due to Arsenic and its mitigation by black tea in Swiss albino mice
Date
2020
Authors
Srivastava, H.M.
Dey, Urmimala
Ghosh, Archismaan
Tripathi, Jai Prakash
Abbas, Syed
Taraphder, A.
Roy, Madhumita
Journal Title
Journal ISSN
Volume Title
Publisher
Alexandria Engineering Journal
Abstract
Inorganic arsenic causes carcinogenesis in a large part of the world. Its potential is elicited by the generation of ROS, which leads to damages to DNA, lipid and protein. Black tea, an antioxidant, can mitigate such deleterious effects by quenching ROS. We study Arsenic-toxicity and its amelioration by black tea in a colony of albino mice: a homology exists between the protein coding regions of mice and human. We observe that black tea has salutary effects on tumor-growth: it arrests damaged cell growth and produces early saturation of the damage. The experimental data obtained by us are modelled with dynamical equations. This is followed by a search for steady states and their stability analysis.
Description
Keywords
Tumor growth dynamics, Immune response, Stability theory
Citation
Srivastava, H. M., Dey, U., Chosh, A., Tripathi, J. P., Abbas, S., Taraphder, A., & Roy, M. (2020). Growth of tumor due to Arsenic and its mitigation by black tea in Swiss albino mice. Alexandria Engineering Journal, 59(3), 1345-1357. https://doi.org/10.1016/j.aej.2020.03.001.