Growth of tumor due to Arsenic and its mitigation by black tea in Swiss albino mice

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dc.contributor.authorSrivastava, H.M.
dc.contributor.authorDey, Urmimala
dc.contributor.authorGhosh, Archismaan
dc.contributor.authorTripathi, Jai Prakash
dc.contributor.authorAbbas, Syed
dc.contributor.authorTaraphder, A.
dc.contributor.authorRoy, Madhumita
dc.date.accessioned2020-09-25T19:09:53Z
dc.date.available2020-09-25T19:09:53Z
dc.date.copyright2020en_US
dc.date.issued2020
dc.description.abstractInorganic arsenic causes carcinogenesis in a large part of the world. Its potential is elicited by the generation of ROS, which leads to damages to DNA, lipid and protein. Black tea, an antioxidant, can mitigate such deleterious effects by quenching ROS. We study Arsenic-toxicity and its amelioration by black tea in a colony of albino mice: a homology exists between the protein coding regions of mice and human. We observe that black tea has salutary effects on tumor-growth: it arrests damaged cell growth and produces early saturation of the damage. The experimental data obtained by us are modelled with dynamical equations. This is followed by a search for steady states and their stability analysis.en_US
dc.description.reviewstatusRevieweden_US
dc.description.scholarlevelFacultyen_US
dc.description.sponsorshipWe would like to thank the reviewers for their comments and suggestions. UD would like to acknowledge the Ministry of Human Resource Development (MHRD), India for research fellowship.en_US
dc.identifier.citationSrivastava, H. M., Dey, U., Chosh, A., Tripathi, J. P., Abbas, S., Taraphder, A., & Roy, M. (2020). Growth of tumor due to Arsenic and its mitigation by black tea in Swiss albino mice. Alexandria Engineering Journal, 59(3), 1345-1357. https://doi.org/10.1016/j.aej.2020.03.001.en_US
dc.identifier.urihttps://doi.org/10.1016/j.aej.2020.03.001
dc.identifier.urihttp://hdl.handle.net/1828/12145
dc.language.isoenen_US
dc.publisherAlexandria Engineering Journalen_US
dc.subjectTumor growth dynamicsen_US
dc.subjectImmune responseen_US
dc.subjectStability theoryen_US
dc.titleGrowth of tumor due to Arsenic and its mitigation by black tea in Swiss albino miceen_US
dc.typeArticleen_US

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